Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis [Corrigendum]
Aydin Y, Koksal AR, Thevenot P, et al. J Hepatocell Carcinoma. 2020;15:1771–1786. The authors have advised due to an error that occurred inadvertently at the time of figure assembly, Figure 3 on page 1587 is incorrect. The high magnification images of Huh-7.5 and HLE should be interchanged...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2022-08-01
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| Series: | Journal of Hepatocellular Carcinoma |
| Subjects: | |
| Online Access: | https://www.dovepress.com/corrigendum-experimental-validation-of-novel-glypican-3-exosomes-for-t-peer-reviewed-fulltext-article-JHC |
| _version_ | 1811276903357612032 |
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| author | Aydin Y Koksal AR Thevenot P Chava S Heidari Z Lin D Sandow T Moroz K Parsi MA Scott J Cohen A Dash S |
| author_facet | Aydin Y Koksal AR Thevenot P Chava S Heidari Z Lin D Sandow T Moroz K Parsi MA Scott J Cohen A Dash S |
| author_sort | Aydin Y |
| collection | DOAJ |
| description | Aydin Y, Koksal AR, Thevenot P, et al. J Hepatocell Carcinoma. 2020;15:1771–1786.
The authors have advised due to an error that occurred inadvertently at the time of figure assembly, Figure 3 on page 1587 is incorrect. The high magnification images of Huh-7.5 and HLE should be interchanged.
The correct Figure 3 is shown below.
Figure 3 Characterization of exosomes released from an autophagy-deficient and an autophagy-competent HCC cell line. (A) Cryogenic transmission electron microscopy (cryoTEM) images of exosomes purified from culture supernatants of autophagy-deficient (Huh-7.5) and autophagy-competent (HLE) HCC lines. Left panel (low magnification). Right panel (high magnification). (B) Top panel: Representative image of exosome Brownian motion in liquid phase using Nanoparticle tracking analysis (NTA). Bottom panel: Size distribution profile of exosomes with mean and mode of the population diameter ± standard error. (C) Exosome concentration in the culture supernatant quantified by NTA. The results are expressed as the mean ± standard deviation and analyzed by Student’s t-test. *P < 0.05. (D) Representative Western blot for TSG101 and CD9 in cell lysates and exosomes isolated from autophagy-deficient Huh-7.5 and autophagy-competent HLE cell cultures. All experiments were performed in triplicate.
The authors apologize for the error and advise it does not affect the results and conclusion of the paper. |
| first_indexed | 2024-04-13T00:06:08Z |
| format | Article |
| id | doaj.art-b82ff58a9f8f4c5ca7f70c21c1cf369c |
| institution | Directory Open Access Journal |
| issn | 2253-5969 |
| language | English |
| last_indexed | 2024-04-13T00:06:08Z |
| publishDate | 2022-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Journal of Hepatocellular Carcinoma |
| spelling | doaj.art-b82ff58a9f8f4c5ca7f70c21c1cf369c2022-12-22T03:11:14ZengDove Medical PressJournal of Hepatocellular Carcinoma2253-59692022-08-01Volume 985385477734Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis [Corrigendum]Aydin YKoksal ARThevenot PChava SHeidari ZLin DSandow TMoroz KParsi MAScott JCohen ADash SAydin Y, Koksal AR, Thevenot P, et al. J Hepatocell Carcinoma. 2020;15:1771–1786. The authors have advised due to an error that occurred inadvertently at the time of figure assembly, Figure 3 on page 1587 is incorrect. The high magnification images of Huh-7.5 and HLE should be interchanged. The correct Figure 3 is shown below. Figure 3 Characterization of exosomes released from an autophagy-deficient and an autophagy-competent HCC cell line. (A) Cryogenic transmission electron microscopy (cryoTEM) images of exosomes purified from culture supernatants of autophagy-deficient (Huh-7.5) and autophagy-competent (HLE) HCC lines. Left panel (low magnification). Right panel (high magnification). (B) Top panel: Representative image of exosome Brownian motion in liquid phase using Nanoparticle tracking analysis (NTA). Bottom panel: Size distribution profile of exosomes with mean and mode of the population diameter ± standard error. (C) Exosome concentration in the culture supernatant quantified by NTA. The results are expressed as the mean ± standard deviation and analyzed by Student’s t-test. *P < 0.05. (D) Representative Western blot for TSG101 and CD9 in cell lysates and exosomes isolated from autophagy-deficient Huh-7.5 and autophagy-competent HLE cell cultures. All experiments were performed in triplicate. The authors apologize for the error and advise it does not affect the results and conclusion of the paper.https://www.dovepress.com/corrigendum-experimental-validation-of-novel-glypican-3-exosomes-for-t-peer-reviewed-fulltext-article-JHChepatocellular carcinomaautophagyexosomeglypican 3surveillance |
| spellingShingle | Aydin Y Koksal AR Thevenot P Chava S Heidari Z Lin D Sandow T Moroz K Parsi MA Scott J Cohen A Dash S Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis [Corrigendum] Journal of Hepatocellular Carcinoma hepatocellular carcinoma autophagy exosome glypican 3 surveillance |
| title | Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis [Corrigendum] |
| title_full | Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis [Corrigendum] |
| title_fullStr | Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis [Corrigendum] |
| title_full_unstemmed | Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis [Corrigendum] |
| title_short | Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis [Corrigendum] |
| title_sort | experimental validation of novel glypican 3 exosomes for the detection of hepatocellular carcinoma in liver cirrhosis corrigendum |
| topic | hepatocellular carcinoma autophagy exosome glypican 3 surveillance |
| url | https://www.dovepress.com/corrigendum-experimental-validation-of-novel-glypican-3-exosomes-for-t-peer-reviewed-fulltext-article-JHC |
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