Human Adipose-Derived Mesenchymal Stromal Cells Injected Systemically into GRMD Dogs without Immunosuppression are Able to Reach the Host Muscle and Express Human Dystrophin

Human Adipose-Derived Mesenchymal Stromal Cells Injected Systemically into GRMD Dogs without Immunosuppression are Able to Reach the Host Muscle and Express Human Dystrophin

Duchenne muscular dystrophy (DMD), a lethal X-linked disorder, is the most common and severe form of muscular dystrophies, affecting 1 in 3,500 male births. Mutations in the DMD gene lead to the absence of muscle dystrophin and a progressive degeneration of skeletal muscle. The possibility to treat...

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Bibliographic Details
Main Authors: N. M. Vieira, M. Valadares, E. Zucconi, M. Secco, C. R. Bueno Junior, V. Brandalise, A. Assoni, J. Gomes, V. Landini, T. Andrade, H. V. A. Caetano, M. Vainzof, M. Zatz
Format: Article
Language:English
Published: SAGE Publishing 2012-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X

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