Diagnostic and therapeutic considerations in Turner syndrome
Newly developed genetic techniques can reveal mosaicism in individuals diagnosed with monosomy X. Noninvasive prenatal diagnosis using maternal blood can detect most fetuses with X chromosome abnormalities. Low-dose and ultralow-dose estrogen replacement therapy can achieve a more physiological endo...
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| Format: | Article |
| Language: | English |
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Korean Society of Pediatric Endocrinology
2017-12-01
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| Series: | Annals of Pediatric Endocrinology & Metabolism |
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| Online Access: | http://e-apem.org/upload/pdf/apem-2017-22-4-226.pdf |
| _version_ | 1811229552904503296 |
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| author | Seung Yang |
| author_facet | Seung Yang |
| author_sort | Seung Yang |
| collection | DOAJ |
| description | Newly developed genetic techniques can reveal mosaicism in individuals diagnosed with monosomy X. Noninvasive prenatal diagnosis using maternal blood can detect most fetuses with X chromosome abnormalities. Low-dose and ultralow-dose estrogen replacement therapy can achieve a more physiological endocrine milieu. However, many complicated and controversial issues with such treatment remain. Therefore, lifetime observation, long-term studies of health problems, and optimal therapeutic plans are needed for women with Turner syndrome. In this review, we discuss several diagnostic trials using recently developed genetic techniques and studies of physiological hormone replacement treatment over the last 5 years. |
| first_indexed | 2024-04-12T10:16:12Z |
| format | Article |
| id | doaj.art-b831ffe0e3e240a0ba913571e0c7d1d3 |
| institution | Directory Open Access Journal |
| issn | 2287-1012 2287-1292 |
| language | English |
| last_indexed | 2024-04-12T10:16:12Z |
| publishDate | 2017-12-01 |
| publisher | Korean Society of Pediatric Endocrinology |
| record_format | Article |
| series | Annals of Pediatric Endocrinology & Metabolism |
| spelling | doaj.art-b831ffe0e3e240a0ba913571e0c7d1d32022-12-22T03:37:12ZengKorean Society of Pediatric EndocrinologyAnnals of Pediatric Endocrinology & Metabolism2287-10122287-12922017-12-0122422623010.6065/apem.2017.22.4.226708Diagnostic and therapeutic considerations in Turner syndromeSeung YangNewly developed genetic techniques can reveal mosaicism in individuals diagnosed with monosomy X. Noninvasive prenatal diagnosis using maternal blood can detect most fetuses with X chromosome abnormalities. Low-dose and ultralow-dose estrogen replacement therapy can achieve a more physiological endocrine milieu. However, many complicated and controversial issues with such treatment remain. Therefore, lifetime observation, long-term studies of health problems, and optimal therapeutic plans are needed for women with Turner syndrome. In this review, we discuss several diagnostic trials using recently developed genetic techniques and studies of physiological hormone replacement treatment over the last 5 years.http://e-apem.org/upload/pdf/apem-2017-22-4-226.pdfTurner syndromeDiagnosisHormone replacement therapy |
| spellingShingle | Seung Yang Diagnostic and therapeutic considerations in Turner syndrome Annals of Pediatric Endocrinology & Metabolism Turner syndrome Diagnosis Hormone replacement therapy |
| title | Diagnostic and therapeutic considerations in Turner syndrome |
| title_full | Diagnostic and therapeutic considerations in Turner syndrome |
| title_fullStr | Diagnostic and therapeutic considerations in Turner syndrome |
| title_full_unstemmed | Diagnostic and therapeutic considerations in Turner syndrome |
| title_short | Diagnostic and therapeutic considerations in Turner syndrome |
| title_sort | diagnostic and therapeutic considerations in turner syndrome |
| topic | Turner syndrome Diagnosis Hormone replacement therapy |
| url | http://e-apem.org/upload/pdf/apem-2017-22-4-226.pdf |
| work_keys_str_mv | AT seungyang diagnosticandtherapeuticconsiderationsinturnersyndrome |