Total Sleep Deprivation Impairs Lateralization of Spatial Working Memory in Young Men
Total sleep deprivation (TSD) negatively affects cognitive function. Previous research has focused on individual variation in cognitive function following TSD, but we know less about how TSD influences the lateralization of spatial working memory. This study used event-related-potential techniques t...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-10-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fnins.2020.562035/full |
| _version_ | 1818848688597893120 |
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| author | Ziyi Peng Cimin Dai Xiaoping Cai Lingjing Zeng Jialu Li Songyue Xie Haiteng Wang Tianyi Yang Yongcong Shao Yongcong Shao Yi Wang Yi Wang |
| author_facet | Ziyi Peng Cimin Dai Xiaoping Cai Lingjing Zeng Jialu Li Songyue Xie Haiteng Wang Tianyi Yang Yongcong Shao Yongcong Shao Yi Wang Yi Wang |
| author_sort | Ziyi Peng |
| collection | DOAJ |
| description | Total sleep deprivation (TSD) negatively affects cognitive function. Previous research has focused on individual variation in cognitive function following TSD, but we know less about how TSD influences the lateralization of spatial working memory. This study used event-related-potential techniques to explore asymmetry in spatial-working-memory impairment. Fourteen healthy male participants performed a two-back task with electroencephalogram (EEG) recordings conducted at baseline and after 36 h of TSD. We selected 12 EEG points corresponding to left and right sides of the brain and then observed changes in N2 and P3 components related to spatial working memory. Before TSD, P3 amplitude differed significantly between the left and right sides of the brain. This difference disappeared after TSD. Compared with baseline, P3 amplitude decreased for a duration as extended as the prolonged latency of N2 components. After 36 h of TSD, P3 amplitude decreased more in the right hemisphere than the left. We therefore conclude that TSD negatively affected spatial working memory, possibly through removing the right hemisphere advantage. |
| first_indexed | 2024-12-19T06:21:19Z |
| format | Article |
| id | doaj.art-b836e1e2cf2d45ed9610ab9fd40f1ebd |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-19T06:21:19Z |
| publishDate | 2020-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-b836e1e2cf2d45ed9610ab9fd40f1ebd2022-12-21T20:32:42ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2020-10-011410.3389/fnins.2020.562035562035Total Sleep Deprivation Impairs Lateralization of Spatial Working Memory in Young MenZiyi Peng0Cimin Dai1Xiaoping Cai2Lingjing Zeng3Jialu Li4Songyue Xie5Haiteng Wang6Tianyi Yang7Yongcong Shao8Yongcong Shao9Yi Wang10Yi Wang11School of Psychology, Beijing Sport University, Beijing, ChinaSchool of Psychology, Beijing Sport University, Beijing, ChinaDepartment of Cadra Word 3 Division, PLA Army General Hospital, Beijing, ChinaSchool of Psychology, Beijing Sport University, Beijing, ChinaSchool of Psychology, Beijing Sport University, Beijing, ChinaSchool of Psychology, Beijing Sport University, Beijing, ChinaSchool of Psychology, Beijing Sport University, Beijing, ChinaSchool of Psychology, Beijing Sport University, Beijing, ChinaSchool of Psychology, Beijing Sport University, Beijing, ChinaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, ChinaChina Institute of Sports and Health Science, Beijing Sport University, Beijing, ChinaState Key Lab of Space Medicine Fundamentals and Application, China Astronaut Research and Training Centre, Beijing, ChinaTotal sleep deprivation (TSD) negatively affects cognitive function. Previous research has focused on individual variation in cognitive function following TSD, but we know less about how TSD influences the lateralization of spatial working memory. This study used event-related-potential techniques to explore asymmetry in spatial-working-memory impairment. Fourteen healthy male participants performed a two-back task with electroencephalogram (EEG) recordings conducted at baseline and after 36 h of TSD. We selected 12 EEG points corresponding to left and right sides of the brain and then observed changes in N2 and P3 components related to spatial working memory. Before TSD, P3 amplitude differed significantly between the left and right sides of the brain. This difference disappeared after TSD. Compared with baseline, P3 amplitude decreased for a duration as extended as the prolonged latency of N2 components. After 36 h of TSD, P3 amplitude decreased more in the right hemisphere than the left. We therefore conclude that TSD negatively affected spatial working memory, possibly through removing the right hemisphere advantage.https://www.frontiersin.org/article/10.3389/fnins.2020.562035/fullsleep deprivationspatial working memoryevent-related potentialslateralizationn-back |
| spellingShingle | Ziyi Peng Cimin Dai Xiaoping Cai Lingjing Zeng Jialu Li Songyue Xie Haiteng Wang Tianyi Yang Yongcong Shao Yongcong Shao Yi Wang Yi Wang Total Sleep Deprivation Impairs Lateralization of Spatial Working Memory in Young Men Frontiers in Neuroscience sleep deprivation spatial working memory event-related potentials lateralization n-back |
| title | Total Sleep Deprivation Impairs Lateralization of Spatial Working Memory in Young Men |
| title_full | Total Sleep Deprivation Impairs Lateralization of Spatial Working Memory in Young Men |
| title_fullStr | Total Sleep Deprivation Impairs Lateralization of Spatial Working Memory in Young Men |
| title_full_unstemmed | Total Sleep Deprivation Impairs Lateralization of Spatial Working Memory in Young Men |
| title_short | Total Sleep Deprivation Impairs Lateralization of Spatial Working Memory in Young Men |
| title_sort | total sleep deprivation impairs lateralization of spatial working memory in young men |
| topic | sleep deprivation spatial working memory event-related potentials lateralization n-back |
| url | https://www.frontiersin.org/article/10.3389/fnins.2020.562035/full |
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