Comparison of Serum Metabolomics Pathways and Patterns between Patients with Major Depressive Disorder with and without Type 2 Diabetes Mellitus: An Exploratory Study

Comparison of Serum Metabolomics Pathways and Patterns between Patients with Major Depressive Disorder with and without Type 2 Diabetes Mellitus: An Exploratory Study

Background: A close relationship exists between major depressive disorder (MDD) and diabetes mellitus. The metabolomic difference and similarity between patients with and without diabetes mellitus have not been well studied in the context of MDD. We aimed to examine these differences and common seru...

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Bibliographic Details
Main Authors: Naomichi Okamoto, Takashi Hoshikawa, Atsuko Ikenouchi, Tomoya Natsuyama, Rintaro Fujii, Ryohei Igata, Hirofumi Tesen, Yuki Konishi, Yuichi Honma, Masaru Harada, Reiji Yoshimura
Format: Article
Language:English
Published: IMR Press 2023-01-01
Series:Journal of Integrative Neuroscience
Subjects:
metabolomics
metabolome
major depressive disorder
type 2 diabetes mellitus
tricarboxylic acid cycle
glutamate metabolism and urea cycle
synthesis and degradation of ketone bodies
taurine and hypotaurine metabolism
Online Access:https://www.imrpress.com/journal/JIN/22/1/10.31083/j.jin2201013

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