Cutaneous Rosai-Dorfman disease: A separate clinical entity

Rosai-Dorfman disease is a benign, self-limited non-Langerhans cell histiocytosis of unknown etiology. Its most common clinical feature is extraordinary massive painless cervical lymphadenopathy. This entity may be limited to the lymph nodes; however, more than 40% of patients have extranodal involv...

Full description

Bibliographic Details
Main Authors: Tiffany Hinojosa, Elmira Ramos, Daniel J. Lewis, Laurent del Angel, Ramya Vangipuram, Andrew J. Peranteau, Stephen K. Tyring
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-07-01
Series:Journal of Dermatology and Dermatologic Surgery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352241017300270
_version_ 1811198247049363456
author Tiffany Hinojosa
Elmira Ramos
Daniel J. Lewis
Laurent del Angel
Ramya Vangipuram
Andrew J. Peranteau
Stephen K. Tyring
author_facet Tiffany Hinojosa
Elmira Ramos
Daniel J. Lewis
Laurent del Angel
Ramya Vangipuram
Andrew J. Peranteau
Stephen K. Tyring
author_sort Tiffany Hinojosa
collection DOAJ
description Rosai-Dorfman disease is a benign, self-limited non-Langerhans cell histiocytosis of unknown etiology. Its most common clinical feature is extraordinary massive painless cervical lymphadenopathy. This entity may be limited to the lymph nodes; however, more than 40% of patients have extranodal involvement, with the skin being the most frequently affected site. Cutaneous disease without the presence of lymphadenopathy is extremely rare but has been reported. We report the intriguing case of exclusively cutaneous Rosai-Dorfman disease in an 80-year-old African-American woman.
first_indexed 2024-04-12T01:28:51Z
format Article
id doaj.art-b83937f290fd41d2a2d288e042543e21
institution Directory Open Access Journal
issn 2352-2410
language English
last_indexed 2024-04-12T01:28:51Z
publishDate 2017-07-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Dermatology and Dermatologic Surgery
spelling doaj.art-b83937f290fd41d2a2d288e042543e212022-12-22T03:53:33ZengWolters Kluwer Medknow PublicationsJournal of Dermatology and Dermatologic Surgery2352-24102017-07-0121210710910.1016/j.jdds.2017.06.005Cutaneous Rosai-Dorfman disease: A separate clinical entityTiffany HinojosaElmira RamosDaniel J. LewisLaurent del AngelRamya VangipuramAndrew J. PeranteauStephen K. TyringRosai-Dorfman disease is a benign, self-limited non-Langerhans cell histiocytosis of unknown etiology. Its most common clinical feature is extraordinary massive painless cervical lymphadenopathy. This entity may be limited to the lymph nodes; however, more than 40% of patients have extranodal involvement, with the skin being the most frequently affected site. Cutaneous disease without the presence of lymphadenopathy is extremely rare but has been reported. We report the intriguing case of exclusively cutaneous Rosai-Dorfman disease in an 80-year-old African-American woman.http://www.sciencedirect.com/science/article/pii/S2352241017300270Rosai-Dorfman diseaseHistiocytosisLymphadenopathyDermatopathology
spellingShingle Tiffany Hinojosa
Elmira Ramos
Daniel J. Lewis
Laurent del Angel
Ramya Vangipuram
Andrew J. Peranteau
Stephen K. Tyring
Cutaneous Rosai-Dorfman disease: A separate clinical entity
Journal of Dermatology and Dermatologic Surgery
Rosai-Dorfman disease
Histiocytosis
Lymphadenopathy
Dermatopathology
title Cutaneous Rosai-Dorfman disease: A separate clinical entity
title_full Cutaneous Rosai-Dorfman disease: A separate clinical entity
title_fullStr Cutaneous Rosai-Dorfman disease: A separate clinical entity
title_full_unstemmed Cutaneous Rosai-Dorfman disease: A separate clinical entity
title_short Cutaneous Rosai-Dorfman disease: A separate clinical entity
title_sort cutaneous rosai dorfman disease a separate clinical entity
topic Rosai-Dorfman disease
Histiocytosis
Lymphadenopathy
Dermatopathology
url http://www.sciencedirect.com/science/article/pii/S2352241017300270
work_keys_str_mv AT tiffanyhinojosa cutaneousrosaidorfmandiseaseaseparateclinicalentity
AT elmiraramos cutaneousrosaidorfmandiseaseaseparateclinicalentity
AT danieljlewis cutaneousrosaidorfmandiseaseaseparateclinicalentity
AT laurentdelangel cutaneousrosaidorfmandiseaseaseparateclinicalentity
AT ramyavangipuram cutaneousrosaidorfmandiseaseaseparateclinicalentity
AT andrewjperanteau cutaneousrosaidorfmandiseaseaseparateclinicalentity
AT stephenktyring cutaneousrosaidorfmandiseaseaseparateclinicalentity