Decreased Superoxide Dismutase Concentrations (SOD) in Plasma and CSF and Increased Circulating Total Antioxidant Capacity (TAC) Are Associated with Unfavorable Neurological Outcome after Aneurysmal Subarachnoid Hemorrhage

Decreased Superoxide Dismutase Concentrations (SOD) in Plasma and CSF and Increased Circulating Total Antioxidant Capacity (TAC) Are Associated with Unfavorable Neurological Outcome after Aneurysmal Subarachnoid Hemorrhage

Background: Subarachnoid hemorrhage (SAH) is a devastating disease with high morbidity and mortality. Hypoxia-induced changes and hemoglobin accumulation within the subarachnoid space are thought to lead to oxidative stress, early brain injury, and delayed vasospasm. This study aimed to evaluate the...

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Bibliographic Details
Main Authors: Harald Krenzlin, Dominik Wesp, Jan Schmitt, Christina Frenz, Elena Kurz, Julia Masomi-Bornwasser, Johannes Lotz, Florian Ringel, Thomas Kerz, Naureen Keric
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Journal of Clinical Medicine
Subjects:
SAH
CSF
plasma
oxidative stress
ROS
antioxidant capacity
Online Access:https://www.mdpi.com/2077-0383/10/6/1188

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https://www.mdpi.com/2077-0383/10/6/1188

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