Triciribine Engages ZFP36L1 and HuR to Stabilize LDLR mRNA

Triciribine Engages ZFP36L1 and HuR to Stabilize LDLR mRNA

An increased understanding of low-density lipoprotein receptor (LDLR) and its regulation may facilitate drug development for the treatment of hypercholesterolemia. Triciribine (TCN), which is a highly selective AKT inhibitor, increases the stability of LDLR mRNA downstream of extracellular signal-re...

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Bibliographic Details
Main Author:	Hilde Sundvold
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Series:	Molecules
Subjects:	AKT LDLR TCN mRNA-stability
Online Access:	https://www.mdpi.com/1420-3049/25/19/4505

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