Cucurbitacin-B Exerts Anticancer Effects through Instigation of Apoptosis and Cell Cycle Arrest within Human Prostate Cancer PC3 Cells via Downregulating JAK/STAT Signaling Cascade

Cucurbitacin-B Exerts Anticancer Effects through Instigation of Apoptosis and Cell Cycle Arrest within Human Prostate Cancer PC3 Cells via Downregulating JAK/STAT Signaling Cascade

Cucurbitacin-B (Cur-B) is an analogue triterpenoid belonging to the Cucurbitaceae family. Previous reports have explicitly outlined various biological activities of Cucurbitaceae family members, including the anticancer activity of Cur-B. In the present study, we tried to elucidate the anticancer ef...

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Bibliographic Details
Main Authors: Ahmed Alafnan, Abdulwahab Alamri, Talib Hussain, Syed Mohd Danish Rizvi
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceuticals
Subjects:
prostate cancer
Cucurbitacin-B
apoptosis
notch signaling
cell cycle arrest
Online Access:https://www.mdpi.com/1424-8247/15/10/1229

Internet

https://www.mdpi.com/1424-8247/15/10/1229

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