Increased risk of psychiatric disorder in patients with hearing loss: a nationwide population-based cohort study
Abstract Background Hearing loss has been shown to be a risk factor for psychiatric disorders. In addition, long-term hearing loss is associated with increased hospitalization and mortality rates; however, the increased risk and duration of effect of hearing loss in combination with other chronic di...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-04-01
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| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-024-04992-4 |
| _version_ | 1797209086539857920 |
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| author | Qun-Yi Nian Chun-An Cheng Li-Hsiang Cheng Yuan-Yung Lin Chin-Hung Wang Wu-Chien Chien Yueng-Hsiang Chu Cheng-Ping Shih Chao-Yin Kuo Hsin-Chien Chen Jih-Chin Lee Chi-Hsiang Chung Wei-Chuan Shangkuan Hung-Che Lin |
| author_facet | Qun-Yi Nian Chun-An Cheng Li-Hsiang Cheng Yuan-Yung Lin Chin-Hung Wang Wu-Chien Chien Yueng-Hsiang Chu Cheng-Ping Shih Chao-Yin Kuo Hsin-Chien Chen Jih-Chin Lee Chi-Hsiang Chung Wei-Chuan Shangkuan Hung-Che Lin |
| author_sort | Qun-Yi Nian |
| collection | DOAJ |
| description | Abstract Background Hearing loss has been shown to be a risk factor for psychiatric disorders. In addition, long-term hearing loss is associated with increased hospitalization and mortality rates; however, the increased risk and duration of effect of hearing loss in combination with other chronic diseases on each psychiatric disorder are still not clearly defined. The purpose of this article is to clarify the risk of hearing loss for each disorder over time. Methods This was a retrospective cohort study, and a national health insurance research database in Taiwan was utilized. All (n = 1,949,101) Taiwanese residents who had a medical visit between 2000 and 2015 were included. Patients with hearing loss and a comparative retrospective cohort were analyzed. Every subject was tracked individually from their index date to identify the subjects who later received a diagnosis of a psychiatric disorder. The Kaplan‒Meier method was used to analyze the cumulative incidence of psychiatric disorders. Cox regression analysis was performed to identify the risk of psychiatric disorders. Results A total of 13,341 (15.42%) and 31,250 (9.03%) patients with and without hearing loss, respectively, were diagnosed with psychiatric disorders (P < 0.001). Multivariate analysis indicated that hearing loss significantly elevated the risk of psychiatric disorders (adjusted HR = 2.587, 95% CI 1.723–3.346, p < 0.001). Conclusion Our findings indicate that patients with hearing loss are more likely to develop psychiatric disorders. Furthermore, the various psychiatric disorders are more likely to occur at different times. Our findings have important clinical implications, including a need for clinicians to implement early intervention for hearing loss and to pay close attention to patients’ psychological status. Trial registration TSGHIRB No. E202216036. |
| first_indexed | 2024-04-24T09:49:07Z |
| format | Article |
| id | doaj.art-b84ad57b903249b8915b4c29a392d3b6 |
| institution | Directory Open Access Journal |
| issn | 1479-5876 |
| language | English |
| last_indexed | 2024-04-24T09:49:07Z |
| publishDate | 2024-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Translational Medicine |
| spelling | doaj.art-b84ad57b903249b8915b4c29a392d3b62024-04-14T11:27:43ZengBMCJournal of Translational Medicine1479-58762024-04-0122111510.1186/s12967-024-04992-4Increased risk of psychiatric disorder in patients with hearing loss: a nationwide population-based cohort studyQun-Yi Nian0Chun-An Cheng1Li-Hsiang Cheng2Yuan-Yung Lin3Chin-Hung Wang4Wu-Chien Chien5Yueng-Hsiang Chu6Cheng-Ping Shih7Chao-Yin Kuo8Hsin-Chien Chen9Jih-Chin Lee10Chi-Hsiang Chung11Wei-Chuan Shangkuan12Hung-Che Lin13Department of Medicine, National Defense Medical CenterDepartment of Neurology, Tri-Service General Hospital, National Defense Medical CenterDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical CenterDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical CenterDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical CenterDepartment of Medical Research, Tri-Service General Hospital, National Defense Medical CenterDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical CenterDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical CenterDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical CenterDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical CenterDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical CenterDepartment of Medical Research, Tri-Service General Hospital, National Defense Medical CenterDepartment of Otolaryngology-Head and Neck Surgery, Taipei City HospitalDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical CenterAbstract Background Hearing loss has been shown to be a risk factor for psychiatric disorders. In addition, long-term hearing loss is associated with increased hospitalization and mortality rates; however, the increased risk and duration of effect of hearing loss in combination with other chronic diseases on each psychiatric disorder are still not clearly defined. The purpose of this article is to clarify the risk of hearing loss for each disorder over time. Methods This was a retrospective cohort study, and a national health insurance research database in Taiwan was utilized. All (n = 1,949,101) Taiwanese residents who had a medical visit between 2000 and 2015 were included. Patients with hearing loss and a comparative retrospective cohort were analyzed. Every subject was tracked individually from their index date to identify the subjects who later received a diagnosis of a psychiatric disorder. The Kaplan‒Meier method was used to analyze the cumulative incidence of psychiatric disorders. Cox regression analysis was performed to identify the risk of psychiatric disorders. Results A total of 13,341 (15.42%) and 31,250 (9.03%) patients with and without hearing loss, respectively, were diagnosed with psychiatric disorders (P < 0.001). Multivariate analysis indicated that hearing loss significantly elevated the risk of psychiatric disorders (adjusted HR = 2.587, 95% CI 1.723–3.346, p < 0.001). Conclusion Our findings indicate that patients with hearing loss are more likely to develop psychiatric disorders. Furthermore, the various psychiatric disorders are more likely to occur at different times. Our findings have important clinical implications, including a need for clinicians to implement early intervention for hearing loss and to pay close attention to patients’ psychological status. Trial registration TSGHIRB No. E202216036.https://doi.org/10.1186/s12967-024-04992-4Psychiatric disorderHearing lossRisk factorPopulation-based retrospective cohort study |
| spellingShingle | Qun-Yi Nian Chun-An Cheng Li-Hsiang Cheng Yuan-Yung Lin Chin-Hung Wang Wu-Chien Chien Yueng-Hsiang Chu Cheng-Ping Shih Chao-Yin Kuo Hsin-Chien Chen Jih-Chin Lee Chi-Hsiang Chung Wei-Chuan Shangkuan Hung-Che Lin Increased risk of psychiatric disorder in patients with hearing loss: a nationwide population-based cohort study Journal of Translational Medicine Psychiatric disorder Hearing loss Risk factor Population-based retrospective cohort study |
| title | Increased risk of psychiatric disorder in patients with hearing loss: a nationwide population-based cohort study |
| title_full | Increased risk of psychiatric disorder in patients with hearing loss: a nationwide population-based cohort study |
| title_fullStr | Increased risk of psychiatric disorder in patients with hearing loss: a nationwide population-based cohort study |
| title_full_unstemmed | Increased risk of psychiatric disorder in patients with hearing loss: a nationwide population-based cohort study |
| title_short | Increased risk of psychiatric disorder in patients with hearing loss: a nationwide population-based cohort study |
| title_sort | increased risk of psychiatric disorder in patients with hearing loss a nationwide population based cohort study |
| topic | Psychiatric disorder Hearing loss Risk factor Population-based retrospective cohort study |
| url | https://doi.org/10.1186/s12967-024-04992-4 |
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