A Design of Experiment Approach to Optimize Spray-Dried Powders Containing <i>Pseudomonas aeruginosa</i><i>Podoviridae</i> and <i>Myoviridae</i> Bacteriophages

A Design of Experiment Approach to Optimize Spray-Dried Powders Containing <i>Pseudomonas aeruginosa</i><i>Podoviridae</i> and <i>Myoviridae</i> Bacteriophages

In the present study, we evaluated the effect of spray-drying formulations and operating parameters of a laboratory-scale spray-dryer on the characteristics of spray-dried powders containing two <i>Pseudomonas aeruginosa</i> bacteriophages exhibiting different morphotypes: a podovirus (L...

Full description

Bibliographic Details
Main Authors:	Emilie Tabare, Tea Glonti, Christel Cochez, Cyrille Ngassam, Jean-Paul Pirnay, Karim Amighi, Jonathan Goole
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Series:	Viruses
Subjects:	DoE QbD antibiotic-resistant bacteriophage therapy spray-drying drying
Online Access:	https://www.mdpi.com/1999-4915/13/10/1926

Similar Items

Eudragit<sup>®</sup> FS Microparticles Containing Bacteriophages, Prepared by Spray-Drying for Oral Administration
by: Emilie Tabare, et al.
Published: (2023-05-01)

Employing QbD strategies to assess the impact of cell viability and density on the primary recovery of monoclonal antibodies
by: Ole Jacob Wohlenberg, et al.
Published: (2023-02-01)

Process Optimization and DOE Application in the Synthesis of Rociletinib Intermediate
by: S. Kapić, et al.
Published: (2018-07-01)

Analysis of the Influence of Process and Formulation Properties on the Drying Behavior of Pharmaceutical Granules in a Semi-Continuous Fluid Bed Drying System
by: Tuur Vandeputte, et al.
Published: (2023-04-01)

Quality by Design (QbD) and Design of Experiments (DOE) as a Strategy for Tuning Lipid Nanoparticle Formulations for RNA Delivery
by: Lidia Gurba-Bryśkiewicz, et al.
Published: (2023-10-01)

The Use of the QbD Approach to Optimize the Co-Loading of Simvastatin and Doxorubicin in Liposomes for a Synergistic Anticancer Effect
by: Cristina-Ioana Barbalata, et al.
Published: (2022-09-01)

A quality by design approach for the development of lyophilized liposomes with simvastatin
by: Alina Porfire, et al.
Published: (2017-11-01)

Brief Note on the Development of Biotechnology
by: Karl Bayer
Published: (2014-01-01)

Quality by Design Approach Using Multiple Linear and Logistic Regression Modeling Enables Microemulsion Scale Up
by: Michele Herneisey, et al.
Published: (2019-05-01)

Formulation Approaches for Improving the Dissolution Behavior and Bioavailability of Tolvaptan Using SMEDDS
by: Jong-Hwa Lee, et al.
Published: (2022-02-01)

AAPS Workshop: accelerating pharmaceutical development through predictive stability approaches, April 4–5, 2016
by: A. L. Freed, et al.
Published: (2017-09-01)

QbD-mediated RP-UPLC method development invoking an FMEA-based risk assessment to estimate nintedanib degradation products and their pathways
by: Balaji Jayagopal, et al.
Published: (2020-09-01)

Satisfying QTPP of Erythropoietin Biosimilar by QbD through DoE-Derived Downstream Process Engineering
by: Kakon Nag, et al.
Published: (2023-08-01)

Editorial: Manufacturing, Formulation and Delivery Issues for Phage Therapy to Become A Reality
by: Danish J. Malik, et al.
Published: (2020-10-01)

Application of Design of Experiments in the Development of Self-Microemulsifying Drug Delivery Systems
by: Chien-Ming Hsieh, et al.
Published: (2023-02-01)

A Screening Study for the Development of Simvastatin-Doxorubicin Liposomes, a Co-Formulation with Future Perspectives in Colon Cancer Therapy
by: Cristina Ioana Barbălată, et al.
Published: (2021-09-01)

Carotenoid containing cationic nanoparticles for effective therapy for suppressing oxidative stress: An intranasal approach
by: Namdev Dhas, et al.
Published: (2023-09-01)

Development and validation of stability indicating UPLC method for the simultaneous estimation of triamterene and hydrochlorothiazide in combined dosage forms using quality by design approach
by: D. Akila Devi, et al.
Published: (2023-02-01)

Quality by design approach for development and validation of a RP-HPLC method for simultaneous estimation of xipamide and valsartan in human plasma
by: Mahmoud M. Sebaiy, et al.
Published: (2022-09-01)

Development and validation of RP-HPLC method for estimation of brexpiprazole in its bulk and tablet dosage form using Quality by Design approach
by: Amol S. Jagdale, et al.
Published: (2021-07-01)

Implementation of QbD strategies in the inoculum expansion of a mAb production process
by: Ole Jacob Böhl, et al.
Published: (2021-03-01)

Broad Bactericidal Activity of the <i>Myoviridae</i> Bacteriophage Lysins LysAm24, LysECD7, and LysSi3 against Gram-Negative ESKAPE Pathogens
by: Nataliia P. Antonova, et al.
Published: (2019-03-01)

Genomic Characterization, Formulation and Efficacy in Planta of a <i>Siphoviridae</i> and <i>Podoviridae</i> Protection Cocktail against the Bacterial Plant Pathogens <i>Pectobacterium</i> spp.
by: Maja A. Zaczek-Moczydłowska, et al.
Published: (2020-01-01)

Lyophilization of Liposomal Formulations: Still Necessary, Still Challenging
by: Silvia Franzé, et al.
Published: (2018-08-01)

Modeling-based Approach Towards Quality by Design for a Telescoped Process
by: This Zahnd, et al.
Published: (2024-03-01)

Phage cocktail containing Podoviridae and Myoviridae bacteriophages inhibits the growth of Pectobacterium spp. under in vitro and in vivo conditions.
by: Maja A Zaczek-Moczydłowska, et al.
Published: (2020-01-01)

Formulation-by-Design of Efinaconazole Spanlastic Nanovesicles for Transungual Delivery Using Statistical Risk Management and Multivariate Analytical Techniques
by: Rashed M. Almuqbil, et al.
Published: (2022-07-01)

Development of Metronidazole Loaded Chitosan Nanoparticles Using QbD Approach—A Novel and Potential Antibacterial Formulation
by: Nagaraja Sreeharsha, et al.
Published: (2020-09-01)

Quality by Design Approach for the Development of Liposome Carrying Ghrelin for Intranasal Administration
by: Cecília de Barros, et al.
Published: (2021-05-01)

Tablet Geometry Effect on the Drug Release Profile from a Hydrogel-Based Drug Delivery System
by: Seyed-Farid Mohseni-Motlagh, et al.
Published: (2023-07-01)

Support Vector Regression Approach to Predict the Design Space for the Extraction Process of Pueraria lobata
by: Yaqi Wang, et al.
Published: (2018-09-01)

Design, Optimization, and Correlation of In Vitro/In Vivo Disintegration of Novel Fast Orally Disintegrating Tablet of High Dose Metformin Hydrochloride Using Moisture Activated Dry Granulation Process and Quality by Design Approach
by: Alhussain H. Aodah, et al.
Published: (2020-06-01)

Abstract P-30: Structure of Bacteriophage SU10 from the Family Podoviridae
by: Marta Šiborová, et al.
Published: (2019-06-01)

Bacteriophage–Antibiotic Combination Therapy against <i>Pseudomonas aeruginosa</i>
by: Guillermo Santamaría-Corral, et al.
Published: (2023-06-01)

Application of a Novel Lytic Podoviridae Phage Pu20 for Biological Control of Drug-Resistant <i>Salmonella</i> in Liquid Eggs
by: Yu Zhang, et al.
Published: (2021-01-01)

Protein profiles of bacteriophages of the family Myoviridae-like induced on M. haemolytica
by: Renata Urban-Chmiel, et al.
Published: (2018-06-01)

Isolation and Characterization of Lytic <i>Pseudomonas aeruginosa</i> Bacteriophages Isolated from Sewage Samples from Tunisia
by: Ismahen Akremi, et al.
Published: (2022-10-01)

Continuous Manufacturing of Solvent-Free Cyclodextrin Inclusion Complexes for Enhanced Drug Solubility via Hot-Melt Extrusion: A Quality by Design Approach
by: Siva Ram Munnangi, et al.
Published: (2023-08-01)

Advances in Twin-Screw Granulation Processing
by: Uttom Nandi, et al.
Published: (2021-04-01)

Quality by design and failure mode and effects analysis applied to the development of electromedical technology: Preliminary results
by: Maria Alexandra Matallana Castellanos, et al.
Published: (2021-12-01)