Large-scale integration of DNA methylation and gene expression array platforms identifies both cis and trans relationships

Large-scale integration of DNA methylation and gene expression array platforms identifies both cis and trans relationships

Although epigenome-wide association studies (EWAS) have been successful in identifying DNA methylation (DNAm) patterns associated with disease states, any further characterization of etiologic mechanisms underlying disease remains elusive. This knowledge gap does not originate from a lack of DNAm–tr...

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Bibliographic Details
Main Authors: Eva E. Lancaster, Vladimir I. Vladimirov, Brien P. Riley, Joseph W. Landry, Roxann Roberson-Nay, Timothy P. York
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Epigenetics
Subjects:
epigenetics
dna methylation
gene expression
transcriptional regulation
multi-omics
data integration
Online Access:http://dx.doi.org/10.1080/15592294.2022.2079293

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