Dissection of multiple sclerosis genetics identifies B and CD4+ T cells as driver cell subsets

Dissection of multiple sclerosis genetics identifies B and CD4+ T cells as driver cell subsets

Abstract Background Multiple sclerosis (MS) is an autoimmune condition of the central nervous system with a well-characterized genetic background. Prior analyses of MS genetics have identified broad enrichments across peripheral immune cells, yet the driver immune subsets are unclear. Results We uti...

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Bibliographic Details
Main Authors: Michael H. Guo, Prashanth Sama, Brenna A. LaBarre, Hrishikesh Lokhande, John Balibalos, Ci Chu, Xiaomi Du, Pouya Kheradpour, Charles C. Kim, Taylor Oniskey, Thomas Snyder, Damien Z. Soghoian, Howard L. Weiner, Tanuja Chitnis, Nikolaos A. Patsopoulos
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-022-02694-y

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