Vaginal Laser Therapy for Female Stress Urinary Incontinence: New Solutions for a Well-Known Issue—A Concise Review

<i>Background and Objectives</i>: Insufficient connective urethra and bladder support related to childbirth and menopausal estrogen decrease leads to stress urinary incontinence (SUI). The aim of this review is to narratively report the efficacy and safety of new mini-invasive solutions...

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Main Authors: Alessandro Ferdinando Ruffolo, Andrea Braga, Marco Torella, Matteo Frigerio, Chiara Cimmino, Andrea De Rosa, Paola Sorice, Fabiana Castronovo, Stefano Salvatore, Maurizio Serati
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/58/4/512
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author Alessandro Ferdinando Ruffolo
Andrea Braga
Marco Torella
Matteo Frigerio
Chiara Cimmino
Andrea De Rosa
Paola Sorice
Fabiana Castronovo
Stefano Salvatore
Maurizio Serati
author_facet Alessandro Ferdinando Ruffolo
Andrea Braga
Marco Torella
Matteo Frigerio
Chiara Cimmino
Andrea De Rosa
Paola Sorice
Fabiana Castronovo
Stefano Salvatore
Maurizio Serati
author_sort Alessandro Ferdinando Ruffolo
collection DOAJ
description <i>Background and Objectives</i>: Insufficient connective urethra and bladder support related to childbirth and menopausal estrogen decrease leads to stress urinary incontinence (SUI). The aim of this review is to narratively report the efficacy and safety of new mini-invasive solutions for SUI treatment as laser energy devices, in particular, the microablative fractional carbon dioxide laser and the non-ablative Erbium-YAG laser. <i>Materials and Methods:</i> For this narrative review, a search of literature from PubMed and EMBASE was performed to evaluate the relevant studies and was limited to English language articles, published from January 2015 to February 2022. <i>Results</i>: A significant subjective improvement, assessed by the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-UI-SF) was reported at the 6-month follow up, with a cure rate ranged from 21% to 38%. A reduction of effect was evidenced between 6 and 24–36 months. Additionally, the 1-h pad weight test evidence a significant objective improvement at the 2–6-month follow up. <i>Conclusions</i>: SUI after vaginal laser therapy resulted statistically improved in almost all studies at short-term follow up, resulting a safe and feasible option in mild SUI. However, cure rates were low, longer-term data actually lacks and the high heterogeneity of methods limits the general recommendations. Larger RCTs evaluating long-term effects are required.
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spelling doaj.art-b8555eb7d487497aa77ca409bd81ed8b2023-12-03T13:41:15ZengMDPI AGMedicina1010-660X1648-91442022-04-0158451210.3390/medicina58040512Vaginal Laser Therapy for Female Stress Urinary Incontinence: New Solutions for a Well-Known Issue—A Concise ReviewAlessandro Ferdinando Ruffolo0Andrea Braga1Marco Torella2Matteo Frigerio3Chiara Cimmino4Andrea De Rosa5Paola Sorice6Fabiana Castronovo7Stefano Salvatore8Maurizio Serati9Obstetrics and Gynecology Unit, IRCCS San Raffaele Hospital, Vita-Salute University, 20132 Milan, ItalyDepartment of Obstetrics and Gynecology, EOC-Beata Vergine Hospital, 6850 Mendrisio, SwitzerlandDepartment of Obstetrics and Gynecology, Second Faculty, 80100 Naples, ItalyASST Monza, Ospedale San Gerardo, 20900 Monza, ItalyDepartment of Obstetrics and Gynecology, Del Ponte Hospital, University of Insubria, 21100 Varese, ItalyDepartment of Obstetrics and Gynecology, Del Ponte Hospital, University of Insubria, 21100 Varese, ItalyDepartment of Obstetrics and Gynecology, Del Ponte Hospital, University of Insubria, 21100 Varese, ItalyDepartment of Obstetrics and Gynecology, EOC-Beata Vergine Hospital, 6850 Mendrisio, SwitzerlandObstetrics and Gynecology Unit, IRCCS San Raffaele Hospital, Vita-Salute University, 20132 Milan, ItalyDepartment of Obstetrics and Gynecology, Del Ponte Hospital, University of Insubria, 21100 Varese, Italy<i>Background and Objectives</i>: Insufficient connective urethra and bladder support related to childbirth and menopausal estrogen decrease leads to stress urinary incontinence (SUI). The aim of this review is to narratively report the efficacy and safety of new mini-invasive solutions for SUI treatment as laser energy devices, in particular, the microablative fractional carbon dioxide laser and the non-ablative Erbium-YAG laser. <i>Materials and Methods:</i> For this narrative review, a search of literature from PubMed and EMBASE was performed to evaluate the relevant studies and was limited to English language articles, published from January 2015 to February 2022. <i>Results</i>: A significant subjective improvement, assessed by the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-UI-SF) was reported at the 6-month follow up, with a cure rate ranged from 21% to 38%. A reduction of effect was evidenced between 6 and 24–36 months. Additionally, the 1-h pad weight test evidence a significant objective improvement at the 2–6-month follow up. <i>Conclusions</i>: SUI after vaginal laser therapy resulted statistically improved in almost all studies at short-term follow up, resulting a safe and feasible option in mild SUI. However, cure rates were low, longer-term data actually lacks and the high heterogeneity of methods limits the general recommendations. Larger RCTs evaluating long-term effects are required.https://www.mdpi.com/1648-9144/58/4/512stress urinary incontinenceurinary incontinenceSUIvaginal laserCO<sub>2</sub> laserCO<sub>2</sub> vaginal laser erbium YAG laser
spellingShingle Alessandro Ferdinando Ruffolo
Andrea Braga
Marco Torella
Matteo Frigerio
Chiara Cimmino
Andrea De Rosa
Paola Sorice
Fabiana Castronovo
Stefano Salvatore
Maurizio Serati
Vaginal Laser Therapy for Female Stress Urinary Incontinence: New Solutions for a Well-Known Issue—A Concise Review
Medicina
stress urinary incontinence
urinary incontinence
SUI
vaginal laser
CO<sub>2</sub> laser
CO<sub>2</sub> vaginal laser erbium YAG laser
title Vaginal Laser Therapy for Female Stress Urinary Incontinence: New Solutions for a Well-Known Issue—A Concise Review
title_full Vaginal Laser Therapy for Female Stress Urinary Incontinence: New Solutions for a Well-Known Issue—A Concise Review
title_fullStr Vaginal Laser Therapy for Female Stress Urinary Incontinence: New Solutions for a Well-Known Issue—A Concise Review
title_full_unstemmed Vaginal Laser Therapy for Female Stress Urinary Incontinence: New Solutions for a Well-Known Issue—A Concise Review
title_short Vaginal Laser Therapy for Female Stress Urinary Incontinence: New Solutions for a Well-Known Issue—A Concise Review
title_sort vaginal laser therapy for female stress urinary incontinence new solutions for a well known issue a concise review
topic stress urinary incontinence
urinary incontinence
SUI
vaginal laser
CO<sub>2</sub> laser
CO<sub>2</sub> vaginal laser erbium YAG laser
url https://www.mdpi.com/1648-9144/58/4/512
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