New-Generation ASiR-V for Dose Reduction While Maintaining Image Quality in CT: A Phantom Study

Over the last few decades, the need to reduce and optimize patient medical radiation exposure has prompted the introduction of novel reconstruction algorithms in computed tomography (CT). Against this backdrop, the present study aimed to assess whether reduced radiation dose CT images reconstructed...

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Main Authors: Sara Ungania, Francesco Maria Solivetti, Marco D’Arienzo, Francesco Quagliani, Isabella Sperduti, Aldo Morrone, Carlo de Mutiis, Vicente Bruzzaniti, Antonino Guerrisi
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/13/9/5639
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author Sara Ungania
Francesco Maria Solivetti
Marco D’Arienzo
Francesco Quagliani
Isabella Sperduti
Aldo Morrone
Carlo de Mutiis
Vicente Bruzzaniti
Antonino Guerrisi
author_facet Sara Ungania
Francesco Maria Solivetti
Marco D’Arienzo
Francesco Quagliani
Isabella Sperduti
Aldo Morrone
Carlo de Mutiis
Vicente Bruzzaniti
Antonino Guerrisi
author_sort Sara Ungania
collection DOAJ
description Over the last few decades, the need to reduce and optimize patient medical radiation exposure has prompted the introduction of novel reconstruction algorithms in computed tomography (CT). Against this backdrop, the present study aimed to assess whether reduced radiation dose CT images reconstructed with the new-generation adaptive statistical iterative reconstruction (ASiR-V) maintain the same image quality as that of routine image reconstruction. In addition, the optimization of image quality parameters for the ASiR-V algorithm (e.g., an optimal combination of blending percentage and noise index (NI)) was investigated. An abdominal reference phantom was imaged using the routine clinical protocol (fixed noise index of 18 and 40% ASiR reconstruction). Reduced radiation dose CT scans were performed with varying NI (22, 24, and 30) and using the ASiR-V reconstruction algorithm. Quantitative and qualitative analyses of image noise, contrast, and resolution were performed against NI and reconstruction blending percentages. Our results confirm the ability of the ASiR-V algorithm to provide images of high diagnostic quality while reducing the patient dose. All the parameters were improved in ASiR-V images as compared to ASiR. Both quantitative and qualitative analyses showed that the best agreement was obtained for the images reconstructed using ASiR-V with NI24 and a high percentage of blending (70–100%). This preliminary study results show that ASiR-V allows for a significant reduction in patient dose (about 40%) while maintaining a good overall image quality when appropriate NI (i.e., 24) is used.
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spelling doaj.art-b856598097444d069e3fdc1511f9e4a32023-11-17T22:36:47ZengMDPI AGApplied Sciences2076-34172023-05-01139563910.3390/app13095639New-Generation ASiR-V for Dose Reduction While Maintaining Image Quality in CT: A Phantom StudySara Ungania0Francesco Maria Solivetti1Marco D’Arienzo2Francesco Quagliani3Isabella Sperduti4Aldo Morrone5Carlo de Mutiis6Vicente Bruzzaniti7Antonino Guerrisi8Laboratory of Medical Physics and Expert System, IRCCS Regina Elena National Cancer Institute, 00144 Rome, ItalyRadiology Unit, IRCCS San Gallicano Dermatological Institute, 00144 Rome, ItalyMedical Physics, ASL Roma 6, 00189 Rome, ItalyLaboratory of Medical Physics and Expert System, IRCCS Regina Elena National Cancer Institute, 00144 Rome, ItalyBiostatistics Unit, IRCCS Regina Elena National Cancer Institute, 00144 Rome, ItalyScientific Direction, IRCCS San Gallicano Dermatological Institute, 00144 Rome, ItalyRadiology Unit, IRCCS San Gallicano Dermatological Institute, 00144 Rome, ItalyLaboratory of Medical Physics and Expert System, IRCCS Regina Elena National Cancer Institute, 00144 Rome, ItalyRadiology Unit, IRCCS San Gallicano Dermatological Institute, 00144 Rome, ItalyOver the last few decades, the need to reduce and optimize patient medical radiation exposure has prompted the introduction of novel reconstruction algorithms in computed tomography (CT). Against this backdrop, the present study aimed to assess whether reduced radiation dose CT images reconstructed with the new-generation adaptive statistical iterative reconstruction (ASiR-V) maintain the same image quality as that of routine image reconstruction. In addition, the optimization of image quality parameters for the ASiR-V algorithm (e.g., an optimal combination of blending percentage and noise index (NI)) was investigated. An abdominal reference phantom was imaged using the routine clinical protocol (fixed noise index of 18 and 40% ASiR reconstruction). Reduced radiation dose CT scans were performed with varying NI (22, 24, and 30) and using the ASiR-V reconstruction algorithm. Quantitative and qualitative analyses of image noise, contrast, and resolution were performed against NI and reconstruction blending percentages. Our results confirm the ability of the ASiR-V algorithm to provide images of high diagnostic quality while reducing the patient dose. All the parameters were improved in ASiR-V images as compared to ASiR. Both quantitative and qualitative analyses showed that the best agreement was obtained for the images reconstructed using ASiR-V with NI24 and a high percentage of blending (70–100%). This preliminary study results show that ASiR-V allows for a significant reduction in patient dose (about 40%) while maintaining a good overall image quality when appropriate NI (i.e., 24) is used.https://www.mdpi.com/2076-3417/13/9/5639X-ray computed tomographyASiRinterventional radiologyiterative reconstruction
spellingShingle Sara Ungania
Francesco Maria Solivetti
Marco D’Arienzo
Francesco Quagliani
Isabella Sperduti
Aldo Morrone
Carlo de Mutiis
Vicente Bruzzaniti
Antonino Guerrisi
New-Generation ASiR-V for Dose Reduction While Maintaining Image Quality in CT: A Phantom Study
Applied Sciences
X-ray computed tomography
ASiR
interventional radiology
iterative reconstruction
title New-Generation ASiR-V for Dose Reduction While Maintaining Image Quality in CT: A Phantom Study
title_full New-Generation ASiR-V for Dose Reduction While Maintaining Image Quality in CT: A Phantom Study
title_fullStr New-Generation ASiR-V for Dose Reduction While Maintaining Image Quality in CT: A Phantom Study
title_full_unstemmed New-Generation ASiR-V for Dose Reduction While Maintaining Image Quality in CT: A Phantom Study
title_short New-Generation ASiR-V for Dose Reduction While Maintaining Image Quality in CT: A Phantom Study
title_sort new generation asir v for dose reduction while maintaining image quality in ct a phantom study
topic X-ray computed tomography
ASiR
interventional radiology
iterative reconstruction
url https://www.mdpi.com/2076-3417/13/9/5639
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