Current understanding of the rational diagnostics and treatment of acquired myasthenia gravis. Part 2: treatment
Due to the fact that acquired myasthenia gravis is an autoimmune disease, so rational treatment of these patients includes the symptomatic therapy (acetylcholinesterase inhibitors, potassium supplements, potassiumsaving diuretics), short-term immunotherapy (intravenous immunoglobulin, methods of ext...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Academician I.P. Pavlov First St. Petersburg State Medical University
2016-09-01
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| Series: | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
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| Online Access: | https://www.sci-notes.ru/jour/article/view/239 |
| _version_ | 1797697559916969984 |
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| author | S. N. Bardakov S. A. Zhivolupov E. R. Barantsevich M. V. Zakharov I. N. Samartsev |
| author_facet | S. N. Bardakov S. A. Zhivolupov E. R. Barantsevich M. V. Zakharov I. N. Samartsev |
| author_sort | S. N. Bardakov |
| collection | DOAJ |
| description | Due to the fact that acquired myasthenia gravis is an autoimmune disease, so rational treatment of these patients includes the symptomatic therapy (acetylcholinesterase inhibitors, potassium supplements, potassiumsaving diuretics), short-term immunotherapy (intravenous immunoglobulin, methods of extracorporeal hemocorrection), longterm immunotherapy (glucocorticosteroids, cytotoxic agents, targeted therapies), thymectomy, as well as a number of new promising therapeutic agents. The choice of effective therapy depends on identifying the clinical forms of myasthenia gravis and a complete analysis of autoimmune mechanisms underlying the disease because of similar clinical forms of myasthenia gravis may respond to similar therapies. |
| first_indexed | 2024-03-12T03:41:56Z |
| format | Article |
| id | doaj.art-b85764c0dbe94e9584c2c87487709d29 |
| institution | Directory Open Access Journal |
| issn | 1607-4181 |
| language | Russian |
| last_indexed | 2024-03-12T03:41:56Z |
| publishDate | 2016-09-01 |
| publisher | Academician I.P. Pavlov First St. Petersburg State Medical University |
| record_format | Article |
| series | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
| spelling | doaj.art-b85764c0dbe94e9584c2c87487709d292023-09-03T13:02:37ZrusAcademician I.P. Pavlov First St. Petersburg State Medical UniversityУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова1607-41812016-09-0123361110.24884/1607-4181-2016-23-3-6-11231Current understanding of the rational diagnostics and treatment of acquired myasthenia gravis. Part 2: treatmentS. N. Bardakov0S. A. Zhivolupov1E. R. Barantsevich2M. V. Zakharov3I. N. Samartsev4Military medical academy of S.M. KirovMilitary medical academy of S.M. KirovPavlov First State Medical University of St. PetersburgMilitary medical academy of S.M. KirovMilitary medical academy of S.M. KirovDue to the fact that acquired myasthenia gravis is an autoimmune disease, so rational treatment of these patients includes the symptomatic therapy (acetylcholinesterase inhibitors, potassium supplements, potassiumsaving diuretics), short-term immunotherapy (intravenous immunoglobulin, methods of extracorporeal hemocorrection), longterm immunotherapy (glucocorticosteroids, cytotoxic agents, targeted therapies), thymectomy, as well as a number of new promising therapeutic agents. The choice of effective therapy depends on identifying the clinical forms of myasthenia gravis and a complete analysis of autoimmune mechanisms underlying the disease because of similar clinical forms of myasthenia gravis may respond to similar therapies.https://www.sci-notes.ru/jour/article/view/239myasthenia gravisseronegative form of myasthenia gravisantibodies to acetylcholine receptorsplasma exchangeimmunosuppressiontreatment algorithmantibodies to antigens of skeletal muscles |
| spellingShingle | S. N. Bardakov S. A. Zhivolupov E. R. Barantsevich M. V. Zakharov I. N. Samartsev Current understanding of the rational diagnostics and treatment of acquired myasthenia gravis. Part 2: treatment Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова myasthenia gravis seronegative form of myasthenia gravis antibodies to acetylcholine receptors plasma exchange immunosuppression treatment algorithm antibodies to antigens of skeletal muscles |
| title | Current understanding of the rational diagnostics and treatment of acquired myasthenia gravis. Part 2: treatment |
| title_full | Current understanding of the rational diagnostics and treatment of acquired myasthenia gravis. Part 2: treatment |
| title_fullStr | Current understanding of the rational diagnostics and treatment of acquired myasthenia gravis. Part 2: treatment |
| title_full_unstemmed | Current understanding of the rational diagnostics and treatment of acquired myasthenia gravis. Part 2: treatment |
| title_short | Current understanding of the rational diagnostics and treatment of acquired myasthenia gravis. Part 2: treatment |
| title_sort | current understanding of the rational diagnostics and treatment of acquired myasthenia gravis part 2 treatment |
| topic | myasthenia gravis seronegative form of myasthenia gravis antibodies to acetylcholine receptors plasma exchange immunosuppression treatment algorithm antibodies to antigens of skeletal muscles |
| url | https://www.sci-notes.ru/jour/article/view/239 |
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