The correlation between facial and eyelid demodicosis. Complex therapeutic approaches

Aim. To assess the correlation between eyelid and facial demodicosis and to develop an optimal anti-parasitic treatment schedule for posterior blepharitis associated with eyelid demodicosis. Materials and methods. 100 patients with posterior blepharitis associated with eyelid demodicosis were enroll...

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Main Authors: D. Yu. Maychuk, M. M. Shokirova, T. A. Simonova, Z. G. Malysheva
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2015-03-01
Series:Oftalʹmologiâ
Subjects:
Online Access:https://www.ophthalmojournal.com/opht/article/view/226
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author D. Yu. Maychuk
M. M. Shokirova
T. A. Simonova
Z. G. Malysheva
author_facet D. Yu. Maychuk
M. M. Shokirova
T. A. Simonova
Z. G. Malysheva
author_sort D. Yu. Maychuk
collection DOAJ
description Aim. To assess the correlation between eyelid and facial demodicosis and to develop an optimal anti-parasitic treatment schedule for posterior blepharitis associated with eyelid demodicosis. Materials and methods. 100 patients with posterior blepharitis associated with eyelid demodicosis were enrolled in the study. The patients were divided into 2 groups depending on Demodex count. Demodex count less than 4 mites was considered normal while Demodex count more than 4 mites was considered pathological. 60 patients with Demodex count more than 4 mites were subdivided into 2 groups. Study group patients (n = 30) received anti-parasitic therapy with preceding anti-inflammatory treatment, eyelid hygiene and massage. Control group patients (n = 30) received antiparasitic therapy only. Patients with verified facial demodicosis received dermatological treatment as well. In all patients, integral indices of subjective discomfort and objective signs of posterior blepharitis were measured, Schirmer’s and Norn’s tests were performed, functional state of meibomian glands was evaluated (compressive test). Results. Eyelid demodicosis was associated with facial demodicosis in 48% of patients. In 10%, Demodex count was less than 4 mites. In 38%, Demodex count was more than 4 mites. Skin lesions were revealed in 1% of patients with Demodex count less than 4 mites and in 20% of patients with Demodex count more than 4 mites. Anti-parasitic therapy with preceding anti-inflammatory treatment, eyelid hygiene and massage improved functional state of meibomian glands and objective signs of posterior meibomian blepharitis. In 1.5 months after the treatment, Demodex was absent in 80% of study group patients and 56.6% of controls. Conclusion. Stepwise treatment of posterior blepharitis associated with eyelid demodicosis (anti-inflammatory and anti-parasitic therapy, eyelid hygiene) is effective and provides prolonged remission.
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spelling doaj.art-b85c0f767981462f9a5050b2a069d4292023-03-13T09:08:36ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452015-03-01121636810.18008/1816-5095-2015-1-63-68221The correlation between facial and eyelid demodicosis. Complex therapeutic approachesD. Yu. Maychuk0M. M. Shokirova1T. A. Simonova2Z. G. Malysheva3Федеральное государственное бюджетное учреждение «Межотраслевой научно-технический комплекс «Микрохирургия глаза» им. акад. С.Н. Федорова» Министерства здравоохранения Российской Федерации, Бескудниковский бульвар, д. 59а, Москва, 127486, РоссияФедеральное государственное бюджетное учреждение «Межотраслевой научно-технический комплекс «Микрохирургия глаза» им. акад. С.Н. Федорова» Министерства здравоохранения Российской Федерации, Бескудниковский бульвар, д. 59а, Москва, 127486, РоссияФедеральное государственное бюджетное учреждение «Межотраслевой научно-технический комплекс «Микрохирургия глаза» им. акад. С.Н. Федорова» Министерства здравоохранения Российской Федерации, Бескудниковский бульвар, д. 59а, Москва, 127486, РоссияФедеральное государственное бюджетное учреждение «Межотраслевой научно-технический комплекс «Микрохирургия глаза» им. акад. С.Н. Федорова» Министерства здравоохранения Российской Федерации, Бескудниковский бульвар, д. 59а, Москва, 127486, РоссияAim. To assess the correlation between eyelid and facial demodicosis and to develop an optimal anti-parasitic treatment schedule for posterior blepharitis associated with eyelid demodicosis. Materials and methods. 100 patients with posterior blepharitis associated with eyelid demodicosis were enrolled in the study. The patients were divided into 2 groups depending on Demodex count. Demodex count less than 4 mites was considered normal while Demodex count more than 4 mites was considered pathological. 60 patients with Demodex count more than 4 mites were subdivided into 2 groups. Study group patients (n = 30) received anti-parasitic therapy with preceding anti-inflammatory treatment, eyelid hygiene and massage. Control group patients (n = 30) received antiparasitic therapy only. Patients with verified facial demodicosis received dermatological treatment as well. In all patients, integral indices of subjective discomfort and objective signs of posterior blepharitis were measured, Schirmer’s and Norn’s tests were performed, functional state of meibomian glands was evaluated (compressive test). Results. Eyelid demodicosis was associated with facial demodicosis in 48% of patients. In 10%, Demodex count was less than 4 mites. In 38%, Demodex count was more than 4 mites. Skin lesions were revealed in 1% of patients with Demodex count less than 4 mites and in 20% of patients with Demodex count more than 4 mites. Anti-parasitic therapy with preceding anti-inflammatory treatment, eyelid hygiene and massage improved functional state of meibomian glands and objective signs of posterior meibomian blepharitis. In 1.5 months after the treatment, Demodex was absent in 80% of study group patients and 56.6% of controls. Conclusion. Stepwise treatment of posterior blepharitis associated with eyelid demodicosis (anti-inflammatory and anti-parasitic therapy, eyelid hygiene) is effective and provides prolonged remission.https://www.ophthalmojournal.com/opht/article/view/226задний блефаритдисфункция мейбомиевых желездемодекозгигиена векпротивовоспалительная терапияпротивопаразитарная терапия
spellingShingle D. Yu. Maychuk
M. M. Shokirova
T. A. Simonova
Z. G. Malysheva
The correlation between facial and eyelid demodicosis. Complex therapeutic approaches
Oftalʹmologiâ
задний блефарит
дисфункция мейбомиевых желез
демодекоз
гигиена век
противовоспалительная терапия
противопаразитарная терапия
title The correlation between facial and eyelid demodicosis. Complex therapeutic approaches
title_full The correlation between facial and eyelid demodicosis. Complex therapeutic approaches
title_fullStr The correlation between facial and eyelid demodicosis. Complex therapeutic approaches
title_full_unstemmed The correlation between facial and eyelid demodicosis. Complex therapeutic approaches
title_short The correlation between facial and eyelid demodicosis. Complex therapeutic approaches
title_sort correlation between facial and eyelid demodicosis complex therapeutic approaches
topic задний блефарит
дисфункция мейбомиевых желез
демодекоз
гигиена век
противовоспалительная терапия
противопаразитарная терапия
url https://www.ophthalmojournal.com/opht/article/view/226
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