miR-511 Deficiency Protects Mice from Experimental Colitis by Reducing TLR3 and TLR4 Responses via WD Repeat and FYVE-Domain-Containing Protein 1

miR-511 Deficiency Protects Mice from Experimental Colitis by Reducing TLR3 and TLR4 Responses via WD Repeat and FYVE-Domain-Containing Protein 1

Antimicrobial responses play an important role in maintaining intestinal heath. Recently we reported that miR-511 may regulate TLR4 responses leading to enhanced intestinal inflammation. However, the exact mechanism remained unclear. In this study we investigated the effect of miR-511 deficiency on...

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Bibliographic Details
Main Authors: Shafaque Rahman, Jolien Vandewalle, Patricia H. P. van Hamersveld, Caroline Verseijden, Olaf Welting, Aldo Jongejan, Pierina Casanova, Sybren L. Meijer, Claude Libert, Theodorus B. M. Hakvoort, Wouter J. de Jonge, Sigrid E. M. Heinsbroek
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
miR-511
intestinal inflammation
mouse
wdfy1
TLRs
Online Access:https://www.mdpi.com/2073-4409/11/1/58

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