Hypochlorous acid antiseptic washout improves patient comfort after intravitreal injection: A patient reported outcomes study
Purpose: Current ocular antiseptic practice for intravitreal injection (IVI) employs 5% povidone–iodine (Betadine®) drops which frequently cause ocular discomfort and prolonged irritation. In an effort to improve comfort while maintaining efficacy, we studied a hypochlorous acid (HOCL 0.01%) spray w...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=11;spage=2439;epage=2444;aulast=Fam |
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| author | Anthony Fam Paul T Finger Ankit S Tomar Gaurav Garg Kimberly J Chin |
| author_facet | Anthony Fam Paul T Finger Ankit S Tomar Gaurav Garg Kimberly J Chin |
| author_sort | Anthony Fam |
| collection | DOAJ |
| description | Purpose: Current ocular antiseptic practice for intravitreal injection (IVI) employs 5% povidone–iodine (Betadine®) drops which frequently cause ocular discomfort and prolonged irritation. In an effort to improve comfort while maintaining efficacy, we studied a hypochlorous acid (HOCL 0.01%) spray washout prior to injection. Methods: Patients had received a minimum of 3 IVIs prepared with Betadine®antisepsis prior to entry in this study. Their subsequent IVIs were prepared with Betadine®followed by HOCL 0.01% washout. Facets of comfort were measured by a Likert-scaled questionnaire to compare their experiences after IVI. Results: Thirty-seven participants were enrolled. Addition of HOCL 0.01% spray after Betadine®reduced the duration of discomfort (P = 0.001) and need for artificial tears postinjection (P = 0.003). It improved their reported quality of life (P = 0.04) and sleep (P = 0.01). There were neither HOCL-related side effects nor endophthalmitis during this study. Conclusion: Topical HOCL 0.01% spray after topical Betadine®antisepsis significantly improved patient comfort following IVIs. |
| first_indexed | 2024-12-13T15:56:58Z |
| format | Article |
| id | doaj.art-b85df0d4f4594702a05e1ed90cc6194d |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-13T15:56:58Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-b85df0d4f4594702a05e1ed90cc6194d2022-12-21T23:39:17ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-0168112439244410.4103/ijo.IJO_2001_20Hypochlorous acid antiseptic washout improves patient comfort after intravitreal injection: A patient reported outcomes studyAnthony FamPaul T FingerAnkit S TomarGaurav GargKimberly J ChinPurpose: Current ocular antiseptic practice for intravitreal injection (IVI) employs 5% povidone–iodine (Betadine®) drops which frequently cause ocular discomfort and prolonged irritation. In an effort to improve comfort while maintaining efficacy, we studied a hypochlorous acid (HOCL 0.01%) spray washout prior to injection. Methods: Patients had received a minimum of 3 IVIs prepared with Betadine®antisepsis prior to entry in this study. Their subsequent IVIs were prepared with Betadine®followed by HOCL 0.01% washout. Facets of comfort were measured by a Likert-scaled questionnaire to compare their experiences after IVI. Results: Thirty-seven participants were enrolled. Addition of HOCL 0.01% spray after Betadine®reduced the duration of discomfort (P = 0.001) and need for artificial tears postinjection (P = 0.003). It improved their reported quality of life (P = 0.04) and sleep (P = 0.01). There were neither HOCL-related side effects nor endophthalmitis during this study. Conclusion: Topical HOCL 0.01% spray after topical Betadine®antisepsis significantly improved patient comfort following IVIs.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=11;spage=2439;epage=2444;aulast=Famantisepsisbetadine®comforthoclhypochlorous acidintravitrealproprophylaxisquality of life |
| spellingShingle | Anthony Fam Paul T Finger Ankit S Tomar Gaurav Garg Kimberly J Chin Hypochlorous acid antiseptic washout improves patient comfort after intravitreal injection: A patient reported outcomes study Indian Journal of Ophthalmology antisepsis betadine® comfort hocl hypochlorous acid intravitreal pro prophylaxis quality of life |
| title | Hypochlorous acid antiseptic washout improves patient comfort after intravitreal injection: A patient reported outcomes study |
| title_full | Hypochlorous acid antiseptic washout improves patient comfort after intravitreal injection: A patient reported outcomes study |
| title_fullStr | Hypochlorous acid antiseptic washout improves patient comfort after intravitreal injection: A patient reported outcomes study |
| title_full_unstemmed | Hypochlorous acid antiseptic washout improves patient comfort after intravitreal injection: A patient reported outcomes study |
| title_short | Hypochlorous acid antiseptic washout improves patient comfort after intravitreal injection: A patient reported outcomes study |
| title_sort | hypochlorous acid antiseptic washout improves patient comfort after intravitreal injection a patient reported outcomes study |
| topic | antisepsis betadine® comfort hocl hypochlorous acid intravitreal pro prophylaxis quality of life |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=11;spage=2439;epage=2444;aulast=Fam |
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