Necrotizing cutaneous zygomycosis by Saksenaea vasiformis in post-COVID-19 individual: A rare case report

We report a rare case of cutaneous zygomycosis by Saksenaea vasiformis in post-COVID-19 individuals. A 55-year-old patient was COVID-19 positive and treated as per the protocols. Following recovery after 5 weeks, presents to the surgery outpatient department with complaints of slowly progressive cut...

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Main Authors: S Prasanna, Mayuri Mahajan, Nikunja Kumar Das, Nikhil Mahajan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:MRIMS Journal of Health Sciences
Subjects:
Online Access:http://www.mrimsjournal.com/article.asp?issn=2321-7006;year=2023;volume=11;issue=2;spage=164;epage=167;aulast=Prasanna
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author S Prasanna
Mayuri Mahajan
Nikunja Kumar Das
Nikhil Mahajan
author_facet S Prasanna
Mayuri Mahajan
Nikunja Kumar Das
Nikhil Mahajan
author_sort S Prasanna
collection DOAJ
description We report a rare case of cutaneous zygomycosis by Saksenaea vasiformis in post-COVID-19 individuals. A 55-year-old patient was COVID-19 positive and treated as per the protocols. Following recovery after 5 weeks, presents to the surgery outpatient department with complaints of slowly progressive cutaneous lesion developed into ulcerative lesion over the left lateral part of the abdomen, hip, and thigh. Based on histopathological and microbiological findings, he was diagnosed with as a case of cutaneous zygomycosis by S. vasiformis. Initially, conservative management with intravenous amphotericin B was given and followed by surgical debridement; later, the patient succumbed. In general, mucormycosis is associated with immunosuppression or debilitating diseases. The mode of entry for molds and spores of zygomycetes is through the respiratory tract through the nose and then reaches the sinuses, orbit, and intracranial structures. Hence, early clinical diagnosis, direct smears, and proper interventions lead to a good prognosis and reduced morbidity caused by zygomycosis. The therapeutic management of fungal infection is quite challenging; hence diagnosing zygomycosis at the earliest will be appropriate, especially in an immunocompromised state. The misusing of prophylactic drugs, steroids, and immunosuppressants for COVID-19 should be avoided and must be used as per protocol and guidelines.
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spelling doaj.art-b85e78b4e7314f4a9fe2f1d0b728a5cf2023-07-21T12:47:29ZengWolters Kluwer Medknow PublicationsMRIMS Journal of Health Sciences2321-70062321-72942023-01-0111216416710.4103/mjhs.mjhs_146_22Necrotizing cutaneous zygomycosis by Saksenaea vasiformis in post-COVID-19 individual: A rare case reportS PrasannaMayuri MahajanNikunja Kumar DasNikhil MahajanWe report a rare case of cutaneous zygomycosis by Saksenaea vasiformis in post-COVID-19 individuals. A 55-year-old patient was COVID-19 positive and treated as per the protocols. Following recovery after 5 weeks, presents to the surgery outpatient department with complaints of slowly progressive cutaneous lesion developed into ulcerative lesion over the left lateral part of the abdomen, hip, and thigh. Based on histopathological and microbiological findings, he was diagnosed with as a case of cutaneous zygomycosis by S. vasiformis. Initially, conservative management with intravenous amphotericin B was given and followed by surgical debridement; later, the patient succumbed. In general, mucormycosis is associated with immunosuppression or debilitating diseases. The mode of entry for molds and spores of zygomycetes is through the respiratory tract through the nose and then reaches the sinuses, orbit, and intracranial structures. Hence, early clinical diagnosis, direct smears, and proper interventions lead to a good prognosis and reduced morbidity caused by zygomycosis. The therapeutic management of fungal infection is quite challenging; hence diagnosing zygomycosis at the earliest will be appropriate, especially in an immunocompromised state. The misusing of prophylactic drugs, steroids, and immunosuppressants for COVID-19 should be avoided and must be used as per protocol and guidelines.http://www.mrimsjournal.com/article.asp?issn=2321-7006;year=2023;volume=11;issue=2;spage=164;epage=167;aulast=Prasannacutaneous zygomycosisimmunosuppressedpost-covid-19saksenaea vasiformis
spellingShingle S Prasanna
Mayuri Mahajan
Nikunja Kumar Das
Nikhil Mahajan
Necrotizing cutaneous zygomycosis by Saksenaea vasiformis in post-COVID-19 individual: A rare case report
MRIMS Journal of Health Sciences
cutaneous zygomycosis
immunosuppressed
post-covid-19
saksenaea vasiformis
title Necrotizing cutaneous zygomycosis by Saksenaea vasiformis in post-COVID-19 individual: A rare case report
title_full Necrotizing cutaneous zygomycosis by Saksenaea vasiformis in post-COVID-19 individual: A rare case report
title_fullStr Necrotizing cutaneous zygomycosis by Saksenaea vasiformis in post-COVID-19 individual: A rare case report
title_full_unstemmed Necrotizing cutaneous zygomycosis by Saksenaea vasiformis in post-COVID-19 individual: A rare case report
title_short Necrotizing cutaneous zygomycosis by Saksenaea vasiformis in post-COVID-19 individual: A rare case report
title_sort necrotizing cutaneous zygomycosis by saksenaea vasiformis in post covid 19 individual a rare case report
topic cutaneous zygomycosis
immunosuppressed
post-covid-19
saksenaea vasiformis
url http://www.mrimsjournal.com/article.asp?issn=2321-7006;year=2023;volume=11;issue=2;spage=164;epage=167;aulast=Prasanna
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AT nikunjakumardas necrotizingcutaneouszygomycosisbysaksenaeavasiformisinpostcovid19individualararecasereport
AT nikhilmahajan necrotizingcutaneouszygomycosisbysaksenaeavasiformisinpostcovid19individualararecasereport