A Rare Variant in <i>MDH2</i> (rs111879470) Is Associated with Predisposition to Recurrent Breast Cancer in an Extended High-Risk Pedigree

A Rare Variant in <i>MDH2</i> (rs111879470) Is Associated with Predisposition to Recurrent Breast Cancer in an Extended High-Risk Pedigree

A significant fraction of breast cancer recurs, with lethal outcome, but specific genetic variants responsible have yet to be identified. Five cousin pairs with recurrent breast cancer from pedigrees with a statistical excess of recurrent breast cancer were sequenced to identify rare, shared candida...

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Bibliographic Details
Main Authors:	Lisa A. Cannon-Albright, Jeff Stevens, Craig C. Teerlink, Julio C. Facelli, Kristina Allen-Brady, Alana L. Welm
Format:	Article
Language:	English
Published:	MDPI AG 2023-12-01
Series:	Cancers
Subjects:	recurrent breast cancer predisposition pedigree UPDB <i>CHEK2</i> <i>PMS2</i>
Online Access:	https://www.mdpi.com/2072-6694/15/24/5851

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