Effect of Endurance Training on Vaspine and Glycemic Indexes in Diabetic Rats
Background and Objectives: Vaspin is an adipokine, which has been derived from and recognized in the visceral fat tissue in rat. In the present study, the effect of endurance training was investigated on vaspin and glycemic indexes of diabetic rats. Methods: In this experimental study, 45 Sprague...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | fas |
| Published: |
Qom University of Medical Sciences
2017-02-01
|
| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
| Subjects: | |
| Online Access: | http://journal.muq.ac.ir/browse.php?a_code=A-10-108-1&slc_lang=en&sid=1 |
| _version_ | 1819131517354377216 |
|---|---|
| author | Syeed Ali Hoseini Abdossaleh Zar Maryam Kheirdeh Ameneh Arayesh |
| author_facet | Syeed Ali Hoseini Abdossaleh Zar Maryam Kheirdeh Ameneh Arayesh |
| author_sort | Syeed Ali Hoseini |
| collection | DOAJ |
| description | Background and Objectives: Vaspin is an adipokine, which has been derived from and recognized in the visceral fat tissue in rat. In the present study, the effect of endurance training was investigated on vaspin and glycemic indexes of diabetic rats.
Methods: In this experimental study, 45 Sprague-Dawley rats were made diabetic by streptozotocin toxin after one week adaptation to laboratory conditions. In the following, after measuring fasting glucose of rats, 30 rats with fasting glucose above 200mg/dl, were selected as statistical sample and randomly divided into three groups (moderate and high intensity training and control). Moderate and high intensity training groups respectively ran on treadmill with no slope for 6 weeks (three 20 minute sessions per week) with the speed of 8-12m/min and 12-18m/min. Data were analyzed using statistical tests of Kolmogorov-Smirnov, one-way ANOVA, and Tukey post-hoc tests. The level of significance was considered as p<0.05.
Results: In this study, high-intensity training has a significant effect on the increase of vaspin. Moderate and high intensity training also had significant effects on the reductions of insulin, fasting glucose, and insulin resistance in diabetic rats.
Conclusion: According to the findings of the present research, it was clarified that endurance training can significantly affect glycemic indexes in diabetic rats. |
| first_indexed | 2024-12-22T09:16:46Z |
| format | Article |
| id | doaj.art-b86321fe5a9d4a9996bedc0e3aaffe0a |
| institution | Directory Open Access Journal |
| issn | 1735-7799 2008-1375 |
| language | fas |
| last_indexed | 2024-12-22T09:16:46Z |
| publishDate | 2017-02-01 |
| publisher | Qom University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
| spelling | doaj.art-b86321fe5a9d4a9996bedc0e3aaffe0a2022-12-21T18:31:18ZfasQom University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum1735-77992008-13752017-02-0110111724Effect of Endurance Training on Vaspine and Glycemic Indexes in Diabetic RatsSyeed Ali Hoseini0Abdossaleh Zar1Maryam Kheirdeh2Ameneh Arayesh3 Islamic Azad University, Marvdasht University of Jahrom , Islamic Azad University, shiraz Branch , Islamic Azad University, shiraz Branch Background and Objectives: Vaspin is an adipokine, which has been derived from and recognized in the visceral fat tissue in rat. In the present study, the effect of endurance training was investigated on vaspin and glycemic indexes of diabetic rats. Methods: In this experimental study, 45 Sprague-Dawley rats were made diabetic by streptozotocin toxin after one week adaptation to laboratory conditions. In the following, after measuring fasting glucose of rats, 30 rats with fasting glucose above 200mg/dl, were selected as statistical sample and randomly divided into three groups (moderate and high intensity training and control). Moderate and high intensity training groups respectively ran on treadmill with no slope for 6 weeks (three 20 minute sessions per week) with the speed of 8-12m/min and 12-18m/min. Data were analyzed using statistical tests of Kolmogorov-Smirnov, one-way ANOVA, and Tukey post-hoc tests. The level of significance was considered as p<0.05. Results: In this study, high-intensity training has a significant effect on the increase of vaspin. Moderate and high intensity training also had significant effects on the reductions of insulin, fasting glucose, and insulin resistance in diabetic rats. Conclusion: According to the findings of the present research, it was clarified that endurance training can significantly affect glycemic indexes in diabetic rats.http://journal.muq.ac.ir/browse.php?a_code=A-10-108-1&slc_lang=en&sid=1exercise vaspin protein rat insulin glucose diabetes mellitus |
| spellingShingle | Syeed Ali Hoseini Abdossaleh Zar Maryam Kheirdeh Ameneh Arayesh Effect of Endurance Training on Vaspine and Glycemic Indexes in Diabetic Rats Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum exercise vaspin protein rat insulin glucose diabetes mellitus |
| title | Effect of Endurance Training on Vaspine and Glycemic Indexes in Diabetic Rats |
| title_full | Effect of Endurance Training on Vaspine and Glycemic Indexes in Diabetic Rats |
| title_fullStr | Effect of Endurance Training on Vaspine and Glycemic Indexes in Diabetic Rats |
| title_full_unstemmed | Effect of Endurance Training on Vaspine and Glycemic Indexes in Diabetic Rats |
| title_short | Effect of Endurance Training on Vaspine and Glycemic Indexes in Diabetic Rats |
| title_sort | effect of endurance training on vaspine and glycemic indexes in diabetic rats |
| topic | exercise vaspin protein rat insulin glucose diabetes mellitus |
| url | http://journal.muq.ac.ir/browse.php?a_code=A-10-108-1&slc_lang=en&sid=1 |
| work_keys_str_mv | AT syeedalihoseini effectofendurancetrainingonvaspineandglycemicindexesindiabeticrats AT abdossalehzar effectofendurancetrainingonvaspineandglycemicindexesindiabeticrats AT maryamkheirdeh effectofendurancetrainingonvaspineandglycemicindexesindiabeticrats AT ameneharayesh effectofendurancetrainingonvaspineandglycemicindexesindiabeticrats |