PHARMACOECONOMICAL APPROVAL OF GENOTYPING ELIGIBILITY IN PATIENTS WITH DIABETES MELLITUS TYPE 2 TAKING METFORMIN
Effectiveness of sugar-lowering therapy depends on both betimes started therapy and genetically defined features of a patient. Single nucleotide polymorphism of genes may be perspective and approved by pharmacoeconomical analyses. We observed 89 patients with newly diagnosed diabetes mellitus type 2...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Remedium Group LLC
2016-12-01
|
| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/1639 |
| Summary: | Effectiveness of sugar-lowering therapy depends on both betimes started therapy and genetically defined features of a patient. Single nucleotide polymorphism of genes may be perspective and approved by pharmacoeconomical analyses. We observed 89 patients with newly diagnosed diabetes mellitus type 2 and 80 subjects without impaired glucose metabolism. We found out 2 types of patients- with “response phenotype“ and “fail phenotype”. CER showed that genotyping before prescribing metformin in order to find out “fail phenotype” to avoid lack of effectiveness could reduce expenses. |
|---|---|
| ISSN: | 2079-701X 2658-5790 |