Rasmussen's encephalitis presenting as focal cortical dysplasia

Rasmussen's encephalitis is a rare syndrome characterized by intractable seizures, often associated with epilepsia partialis continua and symptoms of progressive hemispheric dysfunction. Seizures are usually the hallmark of presentation, but antiepileptic drug treatment fails in most patients a...

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Bibliographic Details
Main Authors: D.J. O'Rourke, A. Bergin, A. Rotenberg, J. Peters, M. Gorman, A. Poduri, J. Cryan, H. Lidov, J. Madsen, C. Harini
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Epilepsy and Behavior Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213323214000103
Description
Summary:Rasmussen's encephalitis is a rare syndrome characterized by intractable seizures, often associated with epilepsia partialis continua and symptoms of progressive hemispheric dysfunction. Seizures are usually the hallmark of presentation, but antiepileptic drug treatment fails in most patients and is ineffective against epilepsia partialis continua, which often requires surgical intervention. Co-occurrence of focal cortical dysplasia has only rarely been described and may have implications regarding pathophysiology and management. We describe a rare case of dual pathology of Rasmussen's encephalitis presenting as a focal cortical dysplasia (FCD) and discuss the literature on this topic.
ISSN:2213-3232