Mechanisms of oligodendrocyte regeneration from ventricular-subventricular zone-derived progenitor cells in white matter diseases

Mechanisms of oligodendrocyte regeneration from ventricular-subventricular zone-derived progenitor cells in white matter diseases

White matter dysfunction is an important part of many CNS disorders including multiple sclerosis and vascular dementia. Within injured areas, myelin loss and oligodendrocyte death may trigger endogenous attempts at regeneration. However, during disease progression, remyelination failure may eventual...

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Bibliographic Details
Main Authors: Takakuni eMaki, Anna C. Liang, Nobukazu eMiyamoto, Eng H. Lo, Ken eArai
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Multiple Sclerosis
Vascular Dementia
demyelination
oligodendrogenesis
Subventricular zone
oligodenrocyte precursor cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00275/full

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