Efficient generation of mNeonGreen Plasmodium falciparum reporter lines enables quantitative fitness analysis
CRISPR editing has enabled the rapid creation of fluorescent Plasmodium transgenic lines, facilitating a deeper understanding of parasite biology. The impact of genetic perturbations such as gene disruption or the introduction of drug resistance alleles on parasite fitness is typically quantified in...
Main Authors: | Johanna Hoshizaki, Hannah Jagoe, Marcus C. S. Lee |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
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Series: | Frontiers in Cellular and Infection Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2022.981432/full |
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