Evaluation of wastewater surveillance for SARS-CoV-2 in Massachusetts correctional facilities, 2020–2022
IntroductionCorrectional facilities have environmental, resource, and organizational factors that facilitate SARS-CoV-2 transmission and challenge clinical testing of staff and residents. In Massachusetts, multiple state prisons implemented wastewater surveillance for strategic testing of individual...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-01-01
|
| Series: | Frontiers in Water |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/frwa.2023.1083316/full |
| _version_ | 1797942771642793984 |
|---|---|
| author | R. Monina Klevens Cristin C. W. Young Scott W. Olesen Anthony Osinski Daniel Church Jennifer Muten Lori Chou Tami Segal Kevin Cranston |
| author_facet | R. Monina Klevens Cristin C. W. Young Scott W. Olesen Anthony Osinski Daniel Church Jennifer Muten Lori Chou Tami Segal Kevin Cranston |
| author_sort | R. Monina Klevens |
| collection | DOAJ |
| description | IntroductionCorrectional facilities have environmental, resource, and organizational factors that facilitate SARS-CoV-2 transmission and challenge clinical testing of staff and residents. In Massachusetts, multiple state prisons implemented wastewater surveillance for strategic testing of individuals and isolation of COVID-19 cases early in the course of infection, as recommended by the Centers for Disease Control and Prevention (CDC). Our objective was to quantify the correlation of COVID-19 cases with facility-level wastewater surveillance compared to standard case surveillance in towns in closest geographic proximity to participating correctional facilities.Materials and methodsAvailable data included number of reported COVID-19 cases in residents from each of eight participating facilities (labeled A-H for anonymity), wastewater viral concentrations at each facility, and COVID-19 cases reported to routine surveillance in towns geographically nearest each facility. We selected data from December 2020-February 2022. Spearman's rank correlation was calculated at each facility to assess agreement between town cases and facility resident cases, and between wastewater concentrations and facility resident cases. We considered a correlation of ≤0.3 as weak and ≥0.6 as strong.ResultsFacilities housed a mean of 502 individuals (range 54–1,184) with mean staffing of 341 (range 53–547). In 7/8 facilities, the town/resident cases correlation coefficients (ρ) were statistically significant (range 0.22–0.65); in all facilities, the wastewater/facility resident cases correlations were statistically significant (range 0.57–0.82). Consistently, ρ values were higher for facility-specific wastewater/resident cases than for town/resident cases: A (0.65, 0.80), B (0.59, 0.81), C (0.55, 0.70), D (0.61, 0.82), E (0.46, 0.62), F (0.51, 0.70), and H (0.22, 0.57).ConclusionWe conclude that wastewater surveillance for SARS-CoV-2 can provide an additional signal to objectively supplement existing COVID-19 clinical surveillance for the early detection of cases and infection control efforts at correctional facilities. |
| first_indexed | 2024-04-10T20:13:49Z |
| format | Article |
| id | doaj.art-b87509a306884e3d8f4afe3b8dae4787 |
| institution | Directory Open Access Journal |
| issn | 2624-9375 |
| language | English |
| last_indexed | 2024-04-10T20:13:49Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Water |
| spelling | doaj.art-b87509a306884e3d8f4afe3b8dae47872023-01-26T08:58:07ZengFrontiers Media S.A.Frontiers in Water2624-93752023-01-01510.3389/frwa.2023.10833161083316Evaluation of wastewater surveillance for SARS-CoV-2 in Massachusetts correctional facilities, 2020–2022R. Monina Klevens0Cristin C. W. Young1Scott W. Olesen2Anthony Osinski3Daniel Church4Jennifer Muten5Lori Chou6Tami Segal7Kevin Cranston8Bureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, United StatesBiobot Analytics, Inc., Cambridge, MA, United StatesBiobot Analytics, Inc., Cambridge, MA, United StatesBureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, United StatesBureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, United StatesBureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, United StatesBureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, United StatesMassachusetts Executive Office of Health and Human Services, Boston, MA, United StatesBureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, United StatesIntroductionCorrectional facilities have environmental, resource, and organizational factors that facilitate SARS-CoV-2 transmission and challenge clinical testing of staff and residents. In Massachusetts, multiple state prisons implemented wastewater surveillance for strategic testing of individuals and isolation of COVID-19 cases early in the course of infection, as recommended by the Centers for Disease Control and Prevention (CDC). Our objective was to quantify the correlation of COVID-19 cases with facility-level wastewater surveillance compared to standard case surveillance in towns in closest geographic proximity to participating correctional facilities.Materials and methodsAvailable data included number of reported COVID-19 cases in residents from each of eight participating facilities (labeled A-H for anonymity), wastewater viral concentrations at each facility, and COVID-19 cases reported to routine surveillance in towns geographically nearest each facility. We selected data from December 2020-February 2022. Spearman's rank correlation was calculated at each facility to assess agreement between town cases and facility resident cases, and between wastewater concentrations and facility resident cases. We considered a correlation of ≤0.3 as weak and ≥0.6 as strong.ResultsFacilities housed a mean of 502 individuals (range 54–1,184) with mean staffing of 341 (range 53–547). In 7/8 facilities, the town/resident cases correlation coefficients (ρ) were statistically significant (range 0.22–0.65); in all facilities, the wastewater/facility resident cases correlations were statistically significant (range 0.57–0.82). Consistently, ρ values were higher for facility-specific wastewater/resident cases than for town/resident cases: A (0.65, 0.80), B (0.59, 0.81), C (0.55, 0.70), D (0.61, 0.82), E (0.46, 0.62), F (0.51, 0.70), and H (0.22, 0.57).ConclusionWe conclude that wastewater surveillance for SARS-CoV-2 can provide an additional signal to objectively supplement existing COVID-19 clinical surveillance for the early detection of cases and infection control efforts at correctional facilities.https://www.frontiersin.org/articles/10.3389/frwa.2023.1083316/fullSARS-CoV-2correctional facilitywastewater-based epidemiologydisease surveillanceCOVID-19 |
| spellingShingle | R. Monina Klevens Cristin C. W. Young Scott W. Olesen Anthony Osinski Daniel Church Jennifer Muten Lori Chou Tami Segal Kevin Cranston Evaluation of wastewater surveillance for SARS-CoV-2 in Massachusetts correctional facilities, 2020–2022 Frontiers in Water SARS-CoV-2 correctional facility wastewater-based epidemiology disease surveillance COVID-19 |
| title | Evaluation of wastewater surveillance for SARS-CoV-2 in Massachusetts correctional facilities, 2020–2022 |
| title_full | Evaluation of wastewater surveillance for SARS-CoV-2 in Massachusetts correctional facilities, 2020–2022 |
| title_fullStr | Evaluation of wastewater surveillance for SARS-CoV-2 in Massachusetts correctional facilities, 2020–2022 |
| title_full_unstemmed | Evaluation of wastewater surveillance for SARS-CoV-2 in Massachusetts correctional facilities, 2020–2022 |
| title_short | Evaluation of wastewater surveillance for SARS-CoV-2 in Massachusetts correctional facilities, 2020–2022 |
| title_sort | evaluation of wastewater surveillance for sars cov 2 in massachusetts correctional facilities 2020 2022 |
| topic | SARS-CoV-2 correctional facility wastewater-based epidemiology disease surveillance COVID-19 |
| url | https://www.frontiersin.org/articles/10.3389/frwa.2023.1083316/full |
| work_keys_str_mv | AT rmoninaklevens evaluationofwastewatersurveillanceforsarscov2inmassachusettscorrectionalfacilities20202022 AT cristincwyoung evaluationofwastewatersurveillanceforsarscov2inmassachusettscorrectionalfacilities20202022 AT scottwolesen evaluationofwastewatersurveillanceforsarscov2inmassachusettscorrectionalfacilities20202022 AT anthonyosinski evaluationofwastewatersurveillanceforsarscov2inmassachusettscorrectionalfacilities20202022 AT danielchurch evaluationofwastewatersurveillanceforsarscov2inmassachusettscorrectionalfacilities20202022 AT jennifermuten evaluationofwastewatersurveillanceforsarscov2inmassachusettscorrectionalfacilities20202022 AT lorichou evaluationofwastewatersurveillanceforsarscov2inmassachusettscorrectionalfacilities20202022 AT tamisegal evaluationofwastewatersurveillanceforsarscov2inmassachusettscorrectionalfacilities20202022 AT kevincranston evaluationofwastewatersurveillanceforsarscov2inmassachusettscorrectionalfacilities20202022 |