Purification and characterization of enterovirus 71 viral particles produced from vero cells grown in a serum-free microcarrier bioreactor system.

Purification and characterization of enterovirus 71 viral particles produced from vero cells grown in a serum-free microcarrier bioreactor system.

BACKGROUND: Enterovirus 71 (EV71) infections manifest most commonly as a childhood exanthema known as hand-foot-and-mouth disease (HFMD) and can cause neurological disease during acute infection. PRINCIPAL FINDING: In this study, we describe the production, purification and characterization of EV71...

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Main Authors: Chia-Chyi Liu, Meng-Shin Guo, Fion Hsiao-Yu Lin, Kuang-Nan Hsiao, Kate Hsuen-Wen Chang, Ai-Hsiang Chou, Yu-Chao Wang, Yu-Ching Chen, Chung-Shi Yang, Pele Choi-Sing Chong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3094384?pdf=render

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