cGAS‐STING Pathway Activation and Systemic Anti‐Tumor Immunity Induction via Photodynamic Nanoparticles with Potent Toxic Platinum DNA Intercalator Against Uveal Melanoma

cGAS‐STING Pathway Activation and Systemic Anti‐Tumor Immunity Induction via Photodynamic Nanoparticles with Potent Toxic Platinum DNA Intercalator Against Uveal Melanoma

Abstract The cGAS‐STING pathway, as a vital innate immune signaling pathway, has attracted considerable attention in tumor immunotherapy research. However, STING agonists are generally incapable of targeting tumors, thus limiting their clinical applications. Here, a photodynamic polymer (P1) is desi...

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Bibliographic Details
Main Authors: Hui Tao, Jia Tan, Hanchen Zhang, Hong Ren, Ziyi Cai, Hanhan Liu, Bingyu Wen, Jiaqi Du, Gaoyang Li, Shijie Chen, Haihua Xiao, Zhihong Deng
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Advanced Science
Subjects:
56MESS
cGAS‐STING
immunotherapy
nanoparticles
uveal melanoma
Online Access:https://doi.org/10.1002/advs.202302895

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