The Protective Effect of Dexmedetomidine Against Ischemia-Reperfusion Injury after Hepatectomy: A Meta-Analysis of Randomized Controlled Trials

The Protective Effect of Dexmedetomidine Against Ischemia-Reperfusion Injury after Hepatectomy: A Meta-Analysis of Randomized Controlled Trials

Background: Hepatic inflow occlusion proceeded to reduce blood loss during hepatectomy induces ischemia-reperfusion (IR) injury in the remnant liver. Dexmedetomidine, a selective α2-adrenoceptor agonist used as an anesthetic adjuvant, has been shown to attenuate IR injury in preclinical and clinical...

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Bibliographic Details
Main Authors:	Ya-Qun Huang, Rui-Ting Wen, Xiao-Tong Li, Jiao Zhang, Zhi-Ying Yu, Yu-Fei Feng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-10-01
Series:	Frontiers in Pharmacology
Subjects:	hepatectomy ischemia-reperfusion injury dexmedetomidine meta-analysis randomized controlled trials
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2021.747911/full

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