Cyclodextrin Inclusion Complexes of Auranofin and Its Iodido Analog: A Chemical and Biological Study

Cyclodextrin Inclusion Complexes of Auranofin and Its Iodido Analog: A Chemical and Biological Study

Auranofin (AF) and its iodido analog, i.e., Au(PEt<sub>3</sub>) I (AFI), were reported to exhibit very promising anticancer properties both in vitro and in vivo. However, both these gold compounds have a scarce aqueous solubility that hampers their pharmaceutical use. Here, we explore wh...

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Bibliographic Details
Main Authors: Damiano Cirri, Ida Landini, Lara Massai, Enrico Mini, Francesca Maestrelli, Luigi Messori
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
auranofin
metal-based drugs
cyclodextrin encapsulation
Online Access:https://www.mdpi.com/1999-4923/13/5/727

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