Genetic immunization for antibody generation in research animals by intravenous delivery of plasmid DNA
Genetic immunization is an attractive approach to generate antibodies because native proteins are expressed in vivo with normal posttranscriptional modifications, avoiding time-consuming and costly antigen isolation or synthesis. Hydrodynamic tail or limb vein delivery of naked plasmid DNA expressio...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2006-02-01
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| Series: | BioTechniques |
| Online Access: | https://www.future-science.com/doi/10.2144/000112088 |