Stigmasterol attenuates hepatic steatosis in rats by strengthening the intestinal barrier and improving bile acid metabolism

Stigmasterol attenuates hepatic steatosis in rats by strengthening the intestinal barrier and improving bile acid metabolism

Abstract Stigmasterol (ST) has been shown to improve both lipid and bile acid (BA) metabolism. However, the mechanism(s) by which ST prevents dyslipidemia via BA metabolism, and the potential involvement of other regulatory mechanisms, remains unclear. Here, we found that ST treatment effectively al...

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Bibliographic Details
Main Authors: Yaxin Zhang, Yuyan Gu, Jing Jiang, Xiaobing Cui, Saibo Cheng, Linling Liu, Zhiyong Huang, Rongxin Liao, Peng Zhao, Jieying Yu, Jing Wang, Yuhua Jia, Wen Jin, Fenghua Zhou
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:npj Science of Food
Online Access:https://doi.org/10.1038/s41538-022-00156-0

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