Corneal Toxicity due to Datura Inoxia
Purpose: To report corneal toxicity following intentional inoculation of the juice of crushed leaves of datura (Datura Inoxia). Case Report: A 70-year-old male presented with diminished vision, redness, watering, and photophobia in his right eye one day before his presentation. The patient had...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Knowledge E
2019-07-01
|
| Series: | Journal of Ophthalmic & Vision Research |
| Subjects: | |
| Online Access: | https://doi.org/10.18502/jovr.v14i3.4792 |
| _version_ | 1828216271474262016 |
|---|---|
| author | Rajesh Subhash Joshi |
| author_facet | Rajesh Subhash Joshi |
| author_sort | Rajesh Subhash Joshi |
| collection | DOAJ |
| description | Purpose: To report corneal toxicity following intentional inoculation of the juice of crushed leaves of datura (Datura Inoxia).
Case Report: A 70-year-old male presented with diminished vision, redness, watering, and photophobia in his right eye one day before his presentation. The patient had instilled the juice of datura leaves in his right eye to treat his ocular problems. Slit lamp examination revealed mild conjunctival and circumcorneal congestion, corneal edema, and folds in Descemet's membrane. The left eye was pseudophakic with an otherwise unremarkable examination. The patient was treated with dexamethasone, cycloplegics, and lubricants. The cornea did not sufficiently recover after one month of treatment leaving him with permanent corneal decompensation that required a referral for keratoplasty. The patient was followed up for six months. We hypothesize damage to the corneal endothelial Na+/K+-ATPase pump by tropane alkaloids as a cause for corneal decompensation.
Conclusion: Awareness about toxicity of this commonly grown plant in the tropics and subtropics is essential in order to avoid blindness due to accidental or deliberate use. |
| first_indexed | 2024-04-12T15:29:31Z |
| format | Article |
| id | doaj.art-b8899de325cc4b7085d2728b36caa0b9 |
| institution | Directory Open Access Journal |
| issn | 2008-322X |
| language | English |
| last_indexed | 2024-04-12T15:29:31Z |
| publishDate | 2019-07-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-b8899de325cc4b7085d2728b36caa0b92022-12-22T03:27:09ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2019-07-01141410.18502/jovr.v14i3.4792jovr.v14i3.4792Corneal Toxicity due to Datura InoxiaRajesh Subhash JoshiPurpose: To report corneal toxicity following intentional inoculation of the juice of crushed leaves of datura (Datura Inoxia). Case Report: A 70-year-old male presented with diminished vision, redness, watering, and photophobia in his right eye one day before his presentation. The patient had instilled the juice of datura leaves in his right eye to treat his ocular problems. Slit lamp examination revealed mild conjunctival and circumcorneal congestion, corneal edema, and folds in Descemet's membrane. The left eye was pseudophakic with an otherwise unremarkable examination. The patient was treated with dexamethasone, cycloplegics, and lubricants. The cornea did not sufficiently recover after one month of treatment leaving him with permanent corneal decompensation that required a referral for keratoplasty. The patient was followed up for six months. We hypothesize damage to the corneal endothelial Na+/K+-ATPase pump by tropane alkaloids as a cause for corneal decompensation. Conclusion: Awareness about toxicity of this commonly grown plant in the tropics and subtropics is essential in order to avoid blindness due to accidental or deliberate use.https://doi.org/10.18502/jovr.v14i3.4792DaturaDatura InoxiaToxic Keratitis |
| spellingShingle | Rajesh Subhash Joshi Corneal Toxicity due to Datura Inoxia Journal of Ophthalmic & Vision Research Datura Datura Inoxia Toxic Keratitis |
| title | Corneal Toxicity due to Datura Inoxia |
| title_full | Corneal Toxicity due to Datura Inoxia |
| title_fullStr | Corneal Toxicity due to Datura Inoxia |
| title_full_unstemmed | Corneal Toxicity due to Datura Inoxia |
| title_short | Corneal Toxicity due to Datura Inoxia |
| title_sort | corneal toxicity due to datura inoxia |
| topic | Datura Datura Inoxia Toxic Keratitis |
| url | https://doi.org/10.18502/jovr.v14i3.4792 |
| work_keys_str_mv | AT rajeshsubhashjoshi cornealtoxicityduetodaturainoxia |