Thrombogram: case report of pseudothrombocytopenia
ABSTRACT The thrombogram is one of the components of the blood count that includes platelet quantification and evaluation. The presence of laboratory artifacts, such as incorrect platelet counts by autoanalyzers, can lead to pseudothrombocytopenia, which is responsible for 15% to 30% of the cases of...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Patologia Clínica
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| Series: | Jornal Brasileiro de Patologia e Medicina Laboratorial |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442020000100701&tlng=pt |
| _version_ | 1819180231099940864 |
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| author | Bruno Miguel B. Costa Maria C. Vellés Maria Mariana F. B. Viana Ana Conceição M. Pereira Susana Catarina P. Rocha Liliana P. Rocha Vera Monica R. P. Moreira |
| author_facet | Bruno Miguel B. Costa Maria C. Vellés Maria Mariana F. B. Viana Ana Conceição M. Pereira Susana Catarina P. Rocha Liliana P. Rocha Vera Monica R. P. Moreira |
| author_sort | Bruno Miguel B. Costa |
| collection | DOAJ |
| description | ABSTRACT The thrombogram is one of the components of the blood count that includes platelet quantification and evaluation. The presence of laboratory artifacts, such as incorrect platelet counts by autoanalyzers, can lead to pseudothrombocytopenia, which is responsible for 15% to 30% of the cases of isolated thrombocytopenia observed in laboratory routine. Pseudothrombocytopenia induced by the anticoagulant ethylenediaminetetraacetic acid (EDTA) is one of the most frequent cases in which the presence of anticoagulant in blood samples can cause platelet aggregation or platelet satellitism. Careful observation of the data emitted by autoanalyzers, such as platelet and flag histograms, is crucial. Other procedures, such as checking for clotting in the sample, repeating the sample and viewing a peripheral blood smear, requesting a new sample taken with another type of anticoagulant, such as citrate, are imperative for the confirmation of cases of pseudothrombocytopenia. |
| first_indexed | 2024-12-22T22:11:03Z |
| format | Article |
| id | doaj.art-b88cf4a882e04fb383adec948dfee826 |
| institution | Directory Open Access Journal |
| issn | 1678-4774 |
| language | English |
| last_indexed | 2024-12-22T22:11:03Z |
| publisher | Sociedade Brasileira de Patologia Clínica |
| record_format | Article |
| series | Jornal Brasileiro de Patologia e Medicina Laboratorial |
| spelling | doaj.art-b88cf4a882e04fb383adec948dfee8262022-12-21T18:10:53ZengSociedade Brasileira de Patologia ClínicaJornal Brasileiro de Patologia e Medicina Laboratorial1678-477410.5935/1676-2444.20200005Thrombogram: case report of pseudothrombocytopeniaBruno Miguel B. CostaMaria C. VellésMaria Mariana F. B. VianaAna Conceição M. PereiraSusana Catarina P. RochaLiliana P. RochaVera Monica R. P. MoreiraABSTRACT The thrombogram is one of the components of the blood count that includes platelet quantification and evaluation. The presence of laboratory artifacts, such as incorrect platelet counts by autoanalyzers, can lead to pseudothrombocytopenia, which is responsible for 15% to 30% of the cases of isolated thrombocytopenia observed in laboratory routine. Pseudothrombocytopenia induced by the anticoagulant ethylenediaminetetraacetic acid (EDTA) is one of the most frequent cases in which the presence of anticoagulant in blood samples can cause platelet aggregation or platelet satellitism. Careful observation of the data emitted by autoanalyzers, such as platelet and flag histograms, is crucial. Other procedures, such as checking for clotting in the sample, repeating the sample and viewing a peripheral blood smear, requesting a new sample taken with another type of anticoagulant, such as citrate, are imperative for the confirmation of cases of pseudothrombocytopenia.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442020000100701&tlng=ptthrombogrampseudothrombocytopeniaanticoagulant |
| spellingShingle | Bruno Miguel B. Costa Maria C. Vellés Maria Mariana F. B. Viana Ana Conceição M. Pereira Susana Catarina P. Rocha Liliana P. Rocha Vera Monica R. P. Moreira Thrombogram: case report of pseudothrombocytopenia Jornal Brasileiro de Patologia e Medicina Laboratorial thrombogram pseudothrombocytopenia anticoagulant |
| title | Thrombogram: case report of pseudothrombocytopenia |
| title_full | Thrombogram: case report of pseudothrombocytopenia |
| title_fullStr | Thrombogram: case report of pseudothrombocytopenia |
| title_full_unstemmed | Thrombogram: case report of pseudothrombocytopenia |
| title_short | Thrombogram: case report of pseudothrombocytopenia |
| title_sort | thrombogram case report of pseudothrombocytopenia |
| topic | thrombogram pseudothrombocytopenia anticoagulant |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442020000100701&tlng=pt |
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