Analysis of Single Nucleotide Variants (SNVs) Induced by Passages of Equine Influenza Virus H3N8 in Embryonated Chicken Eggs

Analysis of Single Nucleotide Variants (SNVs) Induced by Passages of Equine Influenza Virus H3N8 in Embryonated Chicken Eggs

Vaccination is an effective method for the prevention of influenza virus infection. Many manufacturers use embryonated chicken eggs (ECE) for the propagation of vaccine strains. However, the adaptation of viral strains during subsequent passages can lead to additional virus evolution and lower effec...

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Bibliographic Details
Main Authors: Wojciech Rozek, Malgorzata Kwasnik, Wojciech Socha, Pawel Sztromwasser, Jerzy Rola
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Viruses
Subjects:
equine influenza virus
vaccines
genetic variants
NGS
host adaptation
quasispecies
Online Access:https://www.mdpi.com/1999-4915/13/8/1551

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