Manipulation of innate immune signaling pathways by SARS-CoV-2 non-structural proteins

Manipulation of innate immune signaling pathways by SARS-CoV-2 non-structural proteins

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the current coronavirus disease 2019 (COVID-19) pandemic, induces an unbalanced immune response in the host. For instance, the production of type I interferon (IFN) and the response to it, which act as a front-line...

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Bibliographic Details
Main Authors: Yongxu Lu, Hendrik A. Michel, Pei-Hui Wang, Geoffrey L. Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Microbiology
Subjects:
SARS-CoV-2
innate immunity
Nsp6
Orf6
Orf8
IRF3
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1027015/full

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