The value of Persian Weaning Tool in Prediction of patients’ weaning outcome compared with Physician- directed approach: A Diagnostic Accuracy Study

Background: One of the important criteria in patients receiving artificial respiration is the time of weaning from the mechanical ventilator. As physician’s decision might be somehow subjective, several tools have been suggested for prediction of the time of weaning more objectively. This study aime...

Full description

Bibliographic Details
Main Authors: Jamileh Mirzaali, Mohammadali Vakili, Homeira Khoddam
Format: Article
Language:English
Published: Golestan University of Medical Sciences 2020-04-01
Series:Journal of Research Development in Nursing and Midwifery
Subjects:
Online Access:http://goums.ac.ir/jgbfnm/article-1-1181-en.html
_version_ 1828729267795525632
author Jamileh Mirzaali
Mohammadali Vakili
Homeira Khoddam
author_facet Jamileh Mirzaali
Mohammadali Vakili
Homeira Khoddam
author_sort Jamileh Mirzaali
collection DOAJ
description Background: One of the important criteria in patients receiving artificial respiration is the time of weaning from the mechanical ventilator. As physician’s decision might be somehow subjective, several tools have been suggested for prediction of the time of weaning more objectively. This study aimed to determine the predictive value of Persian Weaning Tool (PWT) compared with Physician- directed approach as the gold standard. Methods: This diagnostic accuracy study was done in 2016-2017 in Two Medical and Educational Centers of Gorgan, Iran.  97 admitted patients in intensive care units, under mechanical ventilation were evaluated. The patients were recruited into the study by a convenience sampling method and evaluated for readiness to wean using two approaches (physician’s decision and using PWT). Successful weaning was considered as the ability of patient to breathe spontaneously during the first 48 hours after weaning. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (PLR), and negative likelihood ratio (NLR), as well as the agreement (kappa coefficient) between the two approaches, were calculated. In addition, to compare the differences between variables in two groups, chi-Square, T and man-Whitney tests were used. All analyses were performed using SPSS software ver.16, and MedCalc program ver.13. P<0.05 was considered as statistically significant. Results: Most patients (64.9%) were men. The mean age, duration of hospital admission, and duration of mechanical ventilation of the participants were 46.49±18.15 years, 67.11±7.14 days, and 31.5±2.5 days, respectively. Weaning was successful in 87.6% of the patients. PWT had a significant agreement with the physician’s choice (kappa coefficient=0.637, P<0.001) with sensitivity, specificity, PPV, NPV, PLR, and NLR of 100%, 50%, 93.4%, 100%, 2, and 0, respectively. The cut-off level of 53 was considered as the best point to improve the diagnostic accuracy to 92.94%, 75%, 96.3%, 60%, 3.72, and 0.094, respectively. Conclusions: Findings showed that PWT is an accurate tool for predicting the readiness of patients for weaning objectively. This tool can be used as a complementary approach by physicians and other care providers in intensive care units.
first_indexed 2024-04-12T14:29:59Z
format Article
id doaj.art-b899bbd64fa24d1aab8eb8728af1872c
institution Directory Open Access Journal
issn 2588-3038
language English
last_indexed 2024-04-12T14:29:59Z
publishDate 2020-04-01
publisher Golestan University of Medical Sciences
record_format Article
series Journal of Research Development in Nursing and Midwifery
spelling doaj.art-b899bbd64fa24d1aab8eb8728af1872c2022-12-22T03:29:19ZengGolestan University of Medical SciencesJournal of Research Development in Nursing and Midwifery2588-30382020-04-01171111The value of Persian Weaning Tool in Prediction of patients’ weaning outcome compared with Physician- directed approach: A Diagnostic Accuracy StudyJamileh Mirzaali0Mohammadali Vakili1Homeira Khoddam2 School of nursing and Midwifery, Golestan University of Medical Sciences, Gorgan, Iran. Department of Biostatistics, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran. Nursing Research Center, Golestan University of Medical Sciences, Gorgan, Iran. Background: One of the important criteria in patients receiving artificial respiration is the time of weaning from the mechanical ventilator. As physician’s decision might be somehow subjective, several tools have been suggested for prediction of the time of weaning more objectively. This study aimed to determine the predictive value of Persian Weaning Tool (PWT) compared with Physician- directed approach as the gold standard. Methods: This diagnostic accuracy study was done in 2016-2017 in Two Medical and Educational Centers of Gorgan, Iran.  97 admitted patients in intensive care units, under mechanical ventilation were evaluated. The patients were recruited into the study by a convenience sampling method and evaluated for readiness to wean using two approaches (physician’s decision and using PWT). Successful weaning was considered as the ability of patient to breathe spontaneously during the first 48 hours after weaning. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (PLR), and negative likelihood ratio (NLR), as well as the agreement (kappa coefficient) between the two approaches, were calculated. In addition, to compare the differences between variables in two groups, chi-Square, T and man-Whitney tests were used. All analyses were performed using SPSS software ver.16, and MedCalc program ver.13. P<0.05 was considered as statistically significant. Results: Most patients (64.9%) were men. The mean age, duration of hospital admission, and duration of mechanical ventilation of the participants were 46.49±18.15 years, 67.11±7.14 days, and 31.5±2.5 days, respectively. Weaning was successful in 87.6% of the patients. PWT had a significant agreement with the physician’s choice (kappa coefficient=0.637, P<0.001) with sensitivity, specificity, PPV, NPV, PLR, and NLR of 100%, 50%, 93.4%, 100%, 2, and 0, respectively. The cut-off level of 53 was considered as the best point to improve the diagnostic accuracy to 92.94%, 75%, 96.3%, 60%, 3.72, and 0.094, respectively. Conclusions: Findings showed that PWT is an accurate tool for predicting the readiness of patients for weaning objectively. This tool can be used as a complementary approach by physicians and other care providers in intensive care units.http://goums.ac.ir/jgbfnm/article-1-1181-en.htmlmechanical ventilation weaningpredictive value of testspersiantool
spellingShingle Jamileh Mirzaali
Mohammadali Vakili
Homeira Khoddam
The value of Persian Weaning Tool in Prediction of patients’ weaning outcome compared with Physician- directed approach: A Diagnostic Accuracy Study
Journal of Research Development in Nursing and Midwifery
mechanical ventilation weaning
predictive value of tests
persian
tool
title The value of Persian Weaning Tool in Prediction of patients’ weaning outcome compared with Physician- directed approach: A Diagnostic Accuracy Study
title_full The value of Persian Weaning Tool in Prediction of patients’ weaning outcome compared with Physician- directed approach: A Diagnostic Accuracy Study
title_fullStr The value of Persian Weaning Tool in Prediction of patients’ weaning outcome compared with Physician- directed approach: A Diagnostic Accuracy Study
title_full_unstemmed The value of Persian Weaning Tool in Prediction of patients’ weaning outcome compared with Physician- directed approach: A Diagnostic Accuracy Study
title_short The value of Persian Weaning Tool in Prediction of patients’ weaning outcome compared with Physician- directed approach: A Diagnostic Accuracy Study
title_sort value of persian weaning tool in prediction of patients weaning outcome compared with physician directed approach a diagnostic accuracy study
topic mechanical ventilation weaning
predictive value of tests
persian
tool
url http://goums.ac.ir/jgbfnm/article-1-1181-en.html
work_keys_str_mv AT jamilehmirzaali thevalueofpersianweaningtoolinpredictionofpatientsweaningoutcomecomparedwithphysiciandirectedapproachadiagnosticaccuracystudy
AT mohammadalivakili thevalueofpersianweaningtoolinpredictionofpatientsweaningoutcomecomparedwithphysiciandirectedapproachadiagnosticaccuracystudy
AT homeirakhoddam thevalueofpersianweaningtoolinpredictionofpatientsweaningoutcomecomparedwithphysiciandirectedapproachadiagnosticaccuracystudy
AT jamilehmirzaali valueofpersianweaningtoolinpredictionofpatientsweaningoutcomecomparedwithphysiciandirectedapproachadiagnosticaccuracystudy
AT mohammadalivakili valueofpersianweaningtoolinpredictionofpatientsweaningoutcomecomparedwithphysiciandirectedapproachadiagnosticaccuracystudy
AT homeirakhoddam valueofpersianweaningtoolinpredictionofpatientsweaningoutcomecomparedwithphysiciandirectedapproachadiagnosticaccuracystudy