The Role of Gut and Oral Microbiota in the Formation and Rupture of Intracranial Aneurysms: A Literature Review
In recent years, there has been a growing interest in the role of the microbiome in cardiovascular and cerebrovascular diseases. Emerging research highlights the potential role of the microbiome in intracranial aneurysm (IA) formation and rupture, particularly in relation to inflammation. In this re...
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| Format: | Article |
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MDPI AG
2023-12-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/25/1/48 |
| _version_ | 1797358749963255808 |
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| author | Ann-Kathrin Joerger Carolin Albrecht Veit Rothhammer Klaus Neuhaus Arthur Wagner Bernhard Meyer Maria Wostrack |
| author_facet | Ann-Kathrin Joerger Carolin Albrecht Veit Rothhammer Klaus Neuhaus Arthur Wagner Bernhard Meyer Maria Wostrack |
| author_sort | Ann-Kathrin Joerger |
| collection | DOAJ |
| description | In recent years, there has been a growing interest in the role of the microbiome in cardiovascular and cerebrovascular diseases. Emerging research highlights the potential role of the microbiome in intracranial aneurysm (IA) formation and rupture, particularly in relation to inflammation. In this review, we aim to explore the existing literature regarding the influence of the gut and oral microbiome on IA formation and rupture. In the first section, we provide background information, elucidating the connection between inflammation and aneurysm formation and presenting potential mechanisms of gut–brain interaction. Additionally, we explain the methods for microbiome analysis. The second section reviews existing studies that investigate the relationship between the gut and oral microbiome and IAs. We conclude with a prospective overview, highlighting the extent to which the microbiome is already therapeutically utilized in other fields. Furthermore, we address the challenges associated with the context of IAs that still need to be overcome. |
| first_indexed | 2024-03-08T15:06:39Z |
| format | Article |
| id | doaj.art-b8a484aa7e964e208a8e3eb01f09ac21 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-08T15:06:39Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-b8a484aa7e964e208a8e3eb01f09ac212024-01-10T14:57:58ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-12-012514810.3390/ijms25010048The Role of Gut and Oral Microbiota in the Formation and Rupture of Intracranial Aneurysms: A Literature ReviewAnn-Kathrin Joerger0Carolin Albrecht1Veit Rothhammer2Klaus Neuhaus3Arthur Wagner4Bernhard Meyer5Maria Wostrack6Department of Neurosurgery, Klinikum Rechts der Isar, Technical University, 81675 Munich, GermanyDepartment of Neurosurgery, Klinikum Rechts der Isar, Technical University, 81675 Munich, GermanyDepartment of Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nuremberg, 91054 Erlangen, GermanyCore Facility Microbiom, ZIEL Institute for Food & Health, Technical University of Munich, 85354 Freising, GermanyDepartment of Neurosurgery, Klinikum Rechts der Isar, Technical University, 81675 Munich, GermanyDepartment of Neurosurgery, Klinikum Rechts der Isar, Technical University, 81675 Munich, GermanyDepartment of Neurosurgery, Klinikum Rechts der Isar, Technical University, 81675 Munich, GermanyIn recent years, there has been a growing interest in the role of the microbiome in cardiovascular and cerebrovascular diseases. Emerging research highlights the potential role of the microbiome in intracranial aneurysm (IA) formation and rupture, particularly in relation to inflammation. In this review, we aim to explore the existing literature regarding the influence of the gut and oral microbiome on IA formation and rupture. In the first section, we provide background information, elucidating the connection between inflammation and aneurysm formation and presenting potential mechanisms of gut–brain interaction. Additionally, we explain the methods for microbiome analysis. The second section reviews existing studies that investigate the relationship between the gut and oral microbiome and IAs. We conclude with a prospective overview, highlighting the extent to which the microbiome is already therapeutically utilized in other fields. Furthermore, we address the challenges associated with the context of IAs that still need to be overcome.https://www.mdpi.com/1422-0067/25/1/48oral microbiomegut microbiomebacteriaperiodontitisintracranial aneurysm |
| spellingShingle | Ann-Kathrin Joerger Carolin Albrecht Veit Rothhammer Klaus Neuhaus Arthur Wagner Bernhard Meyer Maria Wostrack The Role of Gut and Oral Microbiota in the Formation and Rupture of Intracranial Aneurysms: A Literature Review International Journal of Molecular Sciences oral microbiome gut microbiome bacteria periodontitis intracranial aneurysm |
| title | The Role of Gut and Oral Microbiota in the Formation and Rupture of Intracranial Aneurysms: A Literature Review |
| title_full | The Role of Gut and Oral Microbiota in the Formation and Rupture of Intracranial Aneurysms: A Literature Review |
| title_fullStr | The Role of Gut and Oral Microbiota in the Formation and Rupture of Intracranial Aneurysms: A Literature Review |
| title_full_unstemmed | The Role of Gut and Oral Microbiota in the Formation and Rupture of Intracranial Aneurysms: A Literature Review |
| title_short | The Role of Gut and Oral Microbiota in the Formation and Rupture of Intracranial Aneurysms: A Literature Review |
| title_sort | role of gut and oral microbiota in the formation and rupture of intracranial aneurysms a literature review |
| topic | oral microbiome gut microbiome bacteria periodontitis intracranial aneurysm |
| url | https://www.mdpi.com/1422-0067/25/1/48 |
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