Antifungal activity from leaf extracts of Cassia alata L., Cassia fistula L. and Cassia tora L.
Crude methanol extracts from leaves of Cassia alata, Cassia fistula and Cassia tora were investigated for their antifungal activities on three pathogenic fungi (Microsporum gypseum, Trichophyton rubrum andPenicillium marneffei). Among 3 species, C. alata was the most effective leaf extract against T...
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| Format: | Article |
| Language: | English |
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Prince of Songkla University
2004-09-01
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| Series: | Songklanakarin Journal of Science and Technology (SJST) |
| Subjects: | |
| Online Access: | http://www.sjst.psu.ac.th/journal/26-5.pdf/13antifungal.pdf |
| _version_ | 1819230303802097664 |
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| author | Metta Ongsakul Souwalak Phongpaichit Vatcharin Rukachaisirikul Nongyao Pujenjob |
| author_facet | Metta Ongsakul Souwalak Phongpaichit Vatcharin Rukachaisirikul Nongyao Pujenjob |
| author_sort | Metta Ongsakul |
| collection | DOAJ |
| description | Crude methanol extracts from leaves of Cassia alata, Cassia fistula and Cassia tora were investigated for their antifungal activities on three pathogenic fungi (Microsporum gypseum, Trichophyton rubrum andPenicillium marneffei). Among 3 species, C. alata was the most effective leaf extract against T. rubrum and M. gypseum with the 50% inhibition concentration (IC50) of hyphal growth at 0.5 and 0.8 mg/ml, respectively, whereas the extract of C. fistula was the most potent inhibitor of P. marneffei with the IC50 of 0.9 mg/ml. In addition, it was found that all three Cassia leaf extracts also affected M. gypseum conidial germination. Microscopic observation revealed that the treated hyphae and macroconidia with leaf extracts were shrunken and collapsed, which might be due to cell fluid leakage. |
| first_indexed | 2024-12-23T11:26:56Z |
| format | Article |
| id | doaj.art-b8a63293481849c88de2a7e0ac2ea643 |
| institution | Directory Open Access Journal |
| issn | 0125-3395 |
| language | English |
| last_indexed | 2024-12-23T11:26:56Z |
| publishDate | 2004-09-01 |
| publisher | Prince of Songkla University |
| record_format | Article |
| series | Songklanakarin Journal of Science and Technology (SJST) |
| spelling | doaj.art-b8a63293481849c88de2a7e0ac2ea6432022-12-21T17:48:55ZengPrince of Songkla UniversitySongklanakarin Journal of Science and Technology (SJST)0125-33952004-09-01265741748Antifungal activity from leaf extracts of Cassia alata L., Cassia fistula L. and Cassia tora L.Metta OngsakulSouwalak PhongpaichitVatcharin RukachaisirikulNongyao PujenjobCrude methanol extracts from leaves of Cassia alata, Cassia fistula and Cassia tora were investigated for their antifungal activities on three pathogenic fungi (Microsporum gypseum, Trichophyton rubrum andPenicillium marneffei). Among 3 species, C. alata was the most effective leaf extract against T. rubrum and M. gypseum with the 50% inhibition concentration (IC50) of hyphal growth at 0.5 and 0.8 mg/ml, respectively, whereas the extract of C. fistula was the most potent inhibitor of P. marneffei with the IC50 of 0.9 mg/ml. In addition, it was found that all three Cassia leaf extracts also affected M. gypseum conidial germination. Microscopic observation revealed that the treated hyphae and macroconidia with leaf extracts were shrunken and collapsed, which might be due to cell fluid leakage.http://www.sjst.psu.ac.th/journal/26-5.pdf/13antifungal.pdfCassia alataCassia fistulaCassia toraantifungal |
| spellingShingle | Metta Ongsakul Souwalak Phongpaichit Vatcharin Rukachaisirikul Nongyao Pujenjob Antifungal activity from leaf extracts of Cassia alata L., Cassia fistula L. and Cassia tora L. Songklanakarin Journal of Science and Technology (SJST) Cassia alata Cassia fistula Cassia tora antifungal |
| title | Antifungal activity from leaf extracts of Cassia alata L., Cassia fistula L. and Cassia tora L. |
| title_full | Antifungal activity from leaf extracts of Cassia alata L., Cassia fistula L. and Cassia tora L. |
| title_fullStr | Antifungal activity from leaf extracts of Cassia alata L., Cassia fistula L. and Cassia tora L. |
| title_full_unstemmed | Antifungal activity from leaf extracts of Cassia alata L., Cassia fistula L. and Cassia tora L. |
| title_short | Antifungal activity from leaf extracts of Cassia alata L., Cassia fistula L. and Cassia tora L. |
| title_sort | antifungal activity from leaf extracts of cassia alata l cassia fistula l and cassia tora l |
| topic | Cassia alata Cassia fistula Cassia tora antifungal |
| url | http://www.sjst.psu.ac.th/journal/26-5.pdf/13antifungal.pdf |
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