Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework
Abstract Background The COVID-19 pandemic has raised concerns of inadvertent SARS-CoV-2 transmission to healthcare workers during routine procedures of the aerodigestive tract in asymptomatic COVID-19 patients. Current efforts to mitigate this risk focus on Personal Protective Equipment, including h...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publications
2020-10-01
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| Series: | Journal of Otolaryngology - Head and Neck Surgery |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40463-020-00474-x |
| _version_ | 1827106375089520640 |
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| author | Syed H. S. Naqvi Martin J. Citardi Davide Cattano Luis Ostrosky-Zeichner Mark I. Knackstedt Ron J. Karni |
| author_facet | Syed H. S. Naqvi Martin J. Citardi Davide Cattano Luis Ostrosky-Zeichner Mark I. Knackstedt Ron J. Karni |
| author_sort | Syed H. S. Naqvi |
| collection | DOAJ |
| description | Abstract Background The COVID-19 pandemic has raised concerns of inadvertent SARS-CoV-2 transmission to healthcare workers during routine procedures of the aerodigestive tract in asymptomatic COVID-19 patients. Current efforts to mitigate this risk focus on Personal Protective Equipment, including high-efficiency filtration as well as other measures. Because the reservoir for SARS-CoV-2 shedding is in the nasopharynx and nasal and oral cavities, the application of viricidal agents to these surfaces may reduce virus burden. Numerous studies have confirmed that povidone-iodine inactivates many common respiratory viruses, including SARS-CoV-1. Povidone-iodine also has good profile for mucosal tolerance. Thus, we propose a prophylactic treatment protocol for the application of topical povidone-iodine to the upper aerodigestive tract. Conclusion Such an approach represents a low-cost, low-morbidity measure that may reduce the risks associated with aerosol-generating procedures performed commonly in otorhinolaryngology operating rooms. Graphical abstract |
| first_indexed | 2024-04-11T02:42:33Z |
| format | Article |
| id | doaj.art-b8a8258ced174b308de07d5baa0f62b1 |
| institution | Directory Open Access Journal |
| issn | 1916-0216 |
| language | English |
| last_indexed | 2025-03-20T09:53:43Z |
| publishDate | 2020-10-01 |
| publisher | SAGE Publications |
| record_format | Article |
| series | Journal of Otolaryngology - Head and Neck Surgery |
| spelling | doaj.art-b8a8258ced174b308de07d5baa0f62b12024-09-24T19:28:06ZengSAGE PublicationsJournal of Otolaryngology - Head and Neck Surgery1916-02162020-10-014911410.1186/s40463-020-00474-xPovidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical frameworkSyed H. S. Naqvi0Martin J. Citardi1Davide Cattano2Luis Ostrosky-Zeichner3Mark I. Knackstedt4Ron J. Karni5Department of Otorhinolaryngology-Head and Neck Surgery, McGovern Medical School, The University of Texas Health Science Center at HoustonDepartment of Otorhinolaryngology-Head and Neck Surgery, McGovern Medical School, The University of Texas Health Science Center at HoustonDepartment of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at HoustonDivision of Infectious Diseases, Department of Medicine, McGovern Medical School, The University of Texas Health Science Center at HoustonDepartment of Otorhinolaryngology-Head and Neck Surgery, McGovern Medical School, The University of Texas Health Science Center at HoustonDepartment of Otorhinolaryngology-Head and Neck Surgery, McGovern Medical School, The University of Texas Health Science Center at HoustonAbstract Background The COVID-19 pandemic has raised concerns of inadvertent SARS-CoV-2 transmission to healthcare workers during routine procedures of the aerodigestive tract in asymptomatic COVID-19 patients. Current efforts to mitigate this risk focus on Personal Protective Equipment, including high-efficiency filtration as well as other measures. Because the reservoir for SARS-CoV-2 shedding is in the nasopharynx and nasal and oral cavities, the application of viricidal agents to these surfaces may reduce virus burden. Numerous studies have confirmed that povidone-iodine inactivates many common respiratory viruses, including SARS-CoV-1. Povidone-iodine also has good profile for mucosal tolerance. Thus, we propose a prophylactic treatment protocol for the application of topical povidone-iodine to the upper aerodigestive tract. Conclusion Such an approach represents a low-cost, low-morbidity measure that may reduce the risks associated with aerosol-generating procedures performed commonly in otorhinolaryngology operating rooms. Graphical abstracthttp://link.springer.com/article/10.1186/s40463-020-00474-xPovidone-iodineBetadineSARS-CoV-2ProphylaxisCOVID-19Upper Aerodigestive tract |
| spellingShingle | Syed H. S. Naqvi Martin J. Citardi Davide Cattano Luis Ostrosky-Zeichner Mark I. Knackstedt Ron J. Karni Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework Journal of Otolaryngology - Head and Neck Surgery Povidone-iodine Betadine SARS-CoV-2 Prophylaxis COVID-19 Upper Aerodigestive tract |
| title | Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework |
| title_full | Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework |
| title_fullStr | Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework |
| title_full_unstemmed | Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework |
| title_short | Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework |
| title_sort | povidone iodine solution as sars cov 2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework |
| topic | Povidone-iodine Betadine SARS-CoV-2 Prophylaxis COVID-19 Upper Aerodigestive tract |
| url | http://link.springer.com/article/10.1186/s40463-020-00474-x |
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