Guillain-Barre syndrome should be monitored upon mass vaccination against SARS-CoV-2

In response to the recent pandemic, vaccines have been developed for large-scale immunization. Despite safety and efficacy verified by health authorities, Guillain-Barre syndrome (GBS) remains a risk of unexpected adverse reactions. Since COVID-19-related GBS cases have largely been reported in Euro...

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Main Author: Char Leung
Format: Article
Language:English
Published: Taylor & Francis Group 2021-09-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2021.1922061
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author Char Leung
author_facet Char Leung
author_sort Char Leung
collection DOAJ
description In response to the recent pandemic, vaccines have been developed for large-scale immunization. Despite safety and efficacy verified by health authorities, Guillain-Barre syndrome (GBS) remains a risk of unexpected adverse reactions. Since COVID-19-related GBS cases have largely been reported in Europe, vaccines involving viral genetic materials can potentially trigger GBS, as demonstrated in clinical trials in the Americas. Therefore, medical professionals should be aware of GBS as a potential adverse reaction in SARS-CoV-2 vaccination. Consultation with a neurologist may be needed. Nevertheless, this is not to say that the use of vaccines against SARS-CoV-2 should be suspended and that the association between GBS and the vaccine is confirmed or excluded. The benefits of vaccine still outweigh potential adverse effects.
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spelling doaj.art-b8ab3142600243e39309d62efe61fd5a2023-09-25T11:22:21ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2021-09-011792957295810.1080/21645515.2021.19220611922061Guillain-Barre syndrome should be monitored upon mass vaccination against SARS-CoV-2Char Leung0Deakin UniversityIn response to the recent pandemic, vaccines have been developed for large-scale immunization. Despite safety and efficacy verified by health authorities, Guillain-Barre syndrome (GBS) remains a risk of unexpected adverse reactions. Since COVID-19-related GBS cases have largely been reported in Europe, vaccines involving viral genetic materials can potentially trigger GBS, as demonstrated in clinical trials in the Americas. Therefore, medical professionals should be aware of GBS as a potential adverse reaction in SARS-CoV-2 vaccination. Consultation with a neurologist may be needed. Nevertheless, this is not to say that the use of vaccines against SARS-CoV-2 should be suspended and that the association between GBS and the vaccine is confirmed or excluded. The benefits of vaccine still outweigh potential adverse effects.http://dx.doi.org/10.1080/21645515.2021.1922061covid-19sars-cov-2guillain-barre syndromevaccine
spellingShingle Char Leung
Guillain-Barre syndrome should be monitored upon mass vaccination against SARS-CoV-2
Human Vaccines & Immunotherapeutics
covid-19
sars-cov-2
guillain-barre syndrome
vaccine
title Guillain-Barre syndrome should be monitored upon mass vaccination against SARS-CoV-2
title_full Guillain-Barre syndrome should be monitored upon mass vaccination against SARS-CoV-2
title_fullStr Guillain-Barre syndrome should be monitored upon mass vaccination against SARS-CoV-2
title_full_unstemmed Guillain-Barre syndrome should be monitored upon mass vaccination against SARS-CoV-2
title_short Guillain-Barre syndrome should be monitored upon mass vaccination against SARS-CoV-2
title_sort guillain barre syndrome should be monitored upon mass vaccination against sars cov 2
topic covid-19
sars-cov-2
guillain-barre syndrome
vaccine
url http://dx.doi.org/10.1080/21645515.2021.1922061
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