The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial
Objective: The objective is to study the role of antibiotic prophylaxis, if any, in the prevention of wound infection after open mesh repair of primary inguinal hernias. Materials and Methods: Patients coming to outpatient department for open mesh repair of inguinal hernia were randomized into the p...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Nigerian Journal of Surgery |
| Subjects: | |
| Online Access: | http://www.nigerianjsurg.com/article.asp?issn=1117-6806;year=2021;volume=27;issue=1;spage=5;epage=8;aulast=Jain |
| _version_ | 1818428414239965184 |
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| author | Sudhir Kumar Jain Tariq Hameed Dhruv Jain Mohak Singh Adiba Nizam |
| author_facet | Sudhir Kumar Jain Tariq Hameed Dhruv Jain Mohak Singh Adiba Nizam |
| author_sort | Sudhir Kumar Jain |
| collection | DOAJ |
| description | Objective: The objective is to study the role of antibiotic prophylaxis, if any, in the prevention of wound infection after open mesh repair of primary inguinal hernias. Materials and Methods: Patients coming to outpatient department for open mesh repair of inguinal hernia were randomized into the placebo group and antibiotic group, a total of 150 patients were enrolled in the study. Follow-up was done up to 1 month to look for any evidence of surgical site infection using the criteria of Centers for Disease Control on wound infection. Results: Twelve patients in the antibiotic group and nine patients in the placebo group were found to have evidence of surgical site infection. This difference was found to be insignificant with P = 0.14. Three patients in the placebo group developed deep surgical site infection but on analysis, this difference was also found to be insignificant with P = 0.122.None of these patients required mesh removal. Conclusion: The result of the present study suggests that the use of prophylactic antibiotics during mesh repair of primary inguinal hernias does not give any extra protection from infections. Multicenter meta-analysis is required to give definite guidelines regarding the use of prophylactic antibiotics. |
| first_indexed | 2024-12-14T15:01:14Z |
| format | Article |
| id | doaj.art-b8acfbc77ce3459aa27e495b8e944288 |
| institution | Directory Open Access Journal |
| issn | 1117-6806 |
| language | English |
| last_indexed | 2024-12-14T15:01:14Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Nigerian Journal of Surgery |
| spelling | doaj.art-b8acfbc77ce3459aa27e495b8e9442882022-12-21T22:56:50ZengWolters Kluwer Medknow PublicationsNigerian Journal of Surgery1117-68062021-01-012715810.4103/njs.NJS_52_19The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trialSudhir Kumar JainTariq HameedDhruv JainMohak SinghAdiba NizamObjective: The objective is to study the role of antibiotic prophylaxis, if any, in the prevention of wound infection after open mesh repair of primary inguinal hernias. Materials and Methods: Patients coming to outpatient department for open mesh repair of inguinal hernia were randomized into the placebo group and antibiotic group, a total of 150 patients were enrolled in the study. Follow-up was done up to 1 month to look for any evidence of surgical site infection using the criteria of Centers for Disease Control on wound infection. Results: Twelve patients in the antibiotic group and nine patients in the placebo group were found to have evidence of surgical site infection. This difference was found to be insignificant with P = 0.14. Three patients in the placebo group developed deep surgical site infection but on analysis, this difference was also found to be insignificant with P = 0.122.None of these patients required mesh removal. Conclusion: The result of the present study suggests that the use of prophylactic antibiotics during mesh repair of primary inguinal hernias does not give any extra protection from infections. Multicenter meta-analysis is required to give definite guidelines regarding the use of prophylactic antibiotics.http://www.nigerianjsurg.com/article.asp?issn=1117-6806;year=2021;volume=27;issue=1;spage=5;epage=8;aulast=Jainantibioticmesh inguinal hernia repairprophylaxis |
| spellingShingle | Sudhir Kumar Jain Tariq Hameed Dhruv Jain Mohak Singh Adiba Nizam The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial Nigerian Journal of Surgery antibiotic mesh inguinal hernia repair prophylaxis |
| title | The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial |
| title_full | The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial |
| title_fullStr | The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial |
| title_full_unstemmed | The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial |
| title_short | The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial |
| title_sort | role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia a prospective double blind randomized placebo controlled trial |
| topic | antibiotic mesh inguinal hernia repair prophylaxis |
| url | http://www.nigerianjsurg.com/article.asp?issn=1117-6806;year=2021;volume=27;issue=1;spage=5;epage=8;aulast=Jain |
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