Haplotype-resolved Chinese male genome assembly based on high-fidelity sequencing

Haplotype-resolved Chinese male genome assembly based on high-fidelity sequencing

The advantages of both the length and accuracy of high-fidelity (HiFi) reads enable chromosome-scale haplotype-resolved genome assembly. In this study, we sequenced a cell line named HJ, established from a Chinese Han male individual by using HiFi and Hi-C. We assembled two high-quality haplotypes o...

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Bibliographic Details
Main Authors: Xiaofei Yang, Xixi Zhao, Shoufang Qu, Peng Jia, Bo Wang, Shenghan Gao, Tun Xu, Wenxin Zhang, Jie Huang, Kai Ye
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2022-11-01
Series:Fundamental Research
Subjects:
Genome assembly
HiFi reads
Human genome
Haplotype-resolved
Chinese Han
Mutation landscape
Online Access:http://www.sciencedirect.com/science/article/pii/S2667325822001145

Internet

http://www.sciencedirect.com/science/article/pii/S2667325822001145

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