High-Throughput NanoBiT-Based Screening for Inhibitors of HIV-1 Vpu and Host BST-2 Protein Interaction

High-Throughput NanoBiT-Based Screening for Inhibitors of HIV-1 Vpu and Host BST-2 Protein Interaction

Bone marrow stromal cell antigen 2 (BST-2), also known as CD317 or tetherin, has been identified as a host restriction factor that suppresses the release of enveloped viruses from host cells by physically tethering viral particles to the cell surface; however, this host defense can be subverted by m...

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Bibliographic Details
Main Authors: Boye Li, Xiaoxiao Dong, Wenmei Zhang, Tian Chen, Boyang Yu, Wenyue Zhao, Yishu Yang, Xiaoli Wang, Qin Hu, Xiayan Wang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
HIV-1
Vpu
BST-2
NanoLuc Binary Technology
high-throughput screening assay
Online Access:https://www.mdpi.com/1422-0067/22/17/9308

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