Neurometabolic therapy in the recovery period of ischemic stroke: impact on quality of life and cognitive functions

Some recovery of impaired neurological functions (a stroke recovery period) is almost always observed within the first 6–24 months after ischemic stroke (IS). The paper discusses the mechanisms responsible for this process (neurogenesis, neuroplasticity, and readaptation) and possible approaches to...

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Main Authors: V. V. Zakharov, N. V. Vakhnina, D. O. Gromova
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2016-07-01
Series:Неврология, нейропсихиатрия, психосоматика
Subjects:
Online Access:https://nnp.ima-press.net/nnp/article/view/614
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author V. V. Zakharov
N. V. Vakhnina
D. O. Gromova
author_facet V. V. Zakharov
N. V. Vakhnina
D. O. Gromova
author_sort V. V. Zakharov
collection DOAJ
description Some recovery of impaired neurological functions (a stroke recovery period) is almost always observed within the first 6–24 months after ischemic stroke (IS). The paper discusses the mechanisms responsible for this process (neurogenesis, neuroplasticity, and readaptation) and possible approaches to the drug support of cerebral reparative processes. It presents data on the rate and etiology of poststroke cognitive impairments (CI) that are one of the important factors that negatively influence the outcome of rehabilitation measures. The results obtained from a recent study of the efficacy of the neurometabolic agent citicoline in the recovery period of IS are given. The use of citicoline is shown to cause a significant regression of CI and to improve quality of life in patients who have sustained IS for the first time.
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spelling doaj.art-b8b12e0c8d624d678c5c6fe870645afb2023-03-13T08:42:15ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422016-07-0182879310.14412/2074-2711-2016-2-87-93561Neurometabolic therapy in the recovery period of ischemic stroke: impact on quality of life and cognitive functionsV. V. Zakharov0N. V. Vakhnina1D. O. Gromova2I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, MoscowI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, MoscowI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, MoscowSome recovery of impaired neurological functions (a stroke recovery period) is almost always observed within the first 6–24 months after ischemic stroke (IS). The paper discusses the mechanisms responsible for this process (neurogenesis, neuroplasticity, and readaptation) and possible approaches to the drug support of cerebral reparative processes. It presents data on the rate and etiology of poststroke cognitive impairments (CI) that are one of the important factors that negatively influence the outcome of rehabilitation measures. The results obtained from a recent study of the efficacy of the neurometabolic agent citicoline in the recovery period of IS are given. The use of citicoline is shown to cause a significant regression of CI and to improve quality of life in patients who have sustained IS for the first time.https://nnp.ima-press.net/nnp/article/view/614strokecognitive impairmentsquality of lifeciticoline
spellingShingle V. V. Zakharov
N. V. Vakhnina
D. O. Gromova
Neurometabolic therapy in the recovery period of ischemic stroke: impact on quality of life and cognitive functions
Неврология, нейропсихиатрия, психосоматика
stroke
cognitive impairments
quality of life
citicoline
title Neurometabolic therapy in the recovery period of ischemic stroke: impact on quality of life and cognitive functions
title_full Neurometabolic therapy in the recovery period of ischemic stroke: impact on quality of life and cognitive functions
title_fullStr Neurometabolic therapy in the recovery period of ischemic stroke: impact on quality of life and cognitive functions
title_full_unstemmed Neurometabolic therapy in the recovery period of ischemic stroke: impact on quality of life and cognitive functions
title_short Neurometabolic therapy in the recovery period of ischemic stroke: impact on quality of life and cognitive functions
title_sort neurometabolic therapy in the recovery period of ischemic stroke impact on quality of life and cognitive functions
topic stroke
cognitive impairments
quality of life
citicoline
url https://nnp.ima-press.net/nnp/article/view/614
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AT nvvakhnina neurometabolictherapyintherecoveryperiodofischemicstrokeimpactonqualityoflifeandcognitivefunctions
AT dogromova neurometabolictherapyintherecoveryperiodofischemicstrokeimpactonqualityoflifeandcognitivefunctions