Serosurvey of hantavirus infection in humans in the border region between Brazil and Argentina
INTRODUCTION: According to reports by the Ministry of Health, in the far western region of the State of Santa Catarina, there have been no reports of hantavirus pulmonary syndrome, a zoonotic disease transmitted by feces of infected rodents. A seroepidemiological study of residents of this region, w...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2011-04-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000200001&lng=en&tlng=en |
| _version_ | 1811244657969987584 |
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| author | William Marciel de Souza Alex Martins Machado Luiz Tadeu Moraes Figueiredo Everton Boff |
| author_facet | William Marciel de Souza Alex Martins Machado Luiz Tadeu Moraes Figueiredo Everton Boff |
| author_sort | William Marciel de Souza |
| collection | DOAJ |
| description | INTRODUCTION: According to reports by the Ministry of Health, in the far western region of the State of Santa Catarina, there have been no reports of hantavirus pulmonary syndrome, a zoonotic disease transmitted by feces of infected rodents. A seroepidemiological study of residents of this region, was conducted, with the aim of determining the presence of hantavirus infections. A total of 340 volunteers of both genus, from the towns of Belmonte and Paraíso, were studied. METHODS: The serum of these patients was collected and used to detect IgG antibodies against recombinant N protein of Araraquara hantavirus, by ELISA assay. The positive samples were then titrated and confirmed by immunofluorescence assay. RESULTS: This study demonstrated the presence of IgG antibodies against hantavirus N protein in 3.5% of the population. The most frequent occupation was farm worker, 81% had direct and indirect contact with rodents, 91.7% of positive cases were farm workers, indicating that the probable cause of infection occurred during barn cleaning. These antibodies are noteworthy, given that the levels of antibodies were verified in individuals whose contact with hantavirus may have occurred many years ago. CONCLUSIONS: This study shows the circulation of hantavirus in the region, a fact that until now, had not reported. All the serum reagents had contact with the pathogen, but did not develop pulmonary and cardiovascular syndrome. It is important to remain alert, because hantavirus is a serious and emerging disease of some relevance. |
| first_indexed | 2024-04-12T14:29:00Z |
| format | Article |
| id | doaj.art-b8baee28c9e84acb86a2de688084289e |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-12T14:29:00Z |
| publishDate | 2011-04-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-b8baee28c9e84acb86a2de688084289e2022-12-22T03:29:21ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492011-04-0144213113510.1590/s0037-86822011005000013S0037-86822011000200001Serosurvey of hantavirus infection in humans in the border region between Brazil and ArgentinaWilliam Marciel de Souza0Alex Martins Machado1Luiz Tadeu Moraes Figueiredo2Everton Boff3Universidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade do Oeste de Santa CatarinaINTRODUCTION: According to reports by the Ministry of Health, in the far western region of the State of Santa Catarina, there have been no reports of hantavirus pulmonary syndrome, a zoonotic disease transmitted by feces of infected rodents. A seroepidemiological study of residents of this region, was conducted, with the aim of determining the presence of hantavirus infections. A total of 340 volunteers of both genus, from the towns of Belmonte and Paraíso, were studied. METHODS: The serum of these patients was collected and used to detect IgG antibodies against recombinant N protein of Araraquara hantavirus, by ELISA assay. The positive samples were then titrated and confirmed by immunofluorescence assay. RESULTS: This study demonstrated the presence of IgG antibodies against hantavirus N protein in 3.5% of the population. The most frequent occupation was farm worker, 81% had direct and indirect contact with rodents, 91.7% of positive cases were farm workers, indicating that the probable cause of infection occurred during barn cleaning. These antibodies are noteworthy, given that the levels of antibodies were verified in individuals whose contact with hantavirus may have occurred many years ago. CONCLUSIONS: This study shows the circulation of hantavirus in the region, a fact that until now, had not reported. All the serum reagents had contact with the pathogen, but did not develop pulmonary and cardiovascular syndrome. It is important to remain alert, because hantavirus is a serious and emerging disease of some relevance.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000200001&lng=en&tlng=enHantavírusSoroprevalência de hantavirose em Santa CatarinaMorbidade |
| spellingShingle | William Marciel de Souza Alex Martins Machado Luiz Tadeu Moraes Figueiredo Everton Boff Serosurvey of hantavirus infection in humans in the border region between Brazil and Argentina Revista da Sociedade Brasileira de Medicina Tropical Hantavírus Soroprevalência de hantavirose em Santa Catarina Morbidade |
| title | Serosurvey of hantavirus infection in humans in the border region between Brazil and Argentina |
| title_full | Serosurvey of hantavirus infection in humans in the border region between Brazil and Argentina |
| title_fullStr | Serosurvey of hantavirus infection in humans in the border region between Brazil and Argentina |
| title_full_unstemmed | Serosurvey of hantavirus infection in humans in the border region between Brazil and Argentina |
| title_short | Serosurvey of hantavirus infection in humans in the border region between Brazil and Argentina |
| title_sort | serosurvey of hantavirus infection in humans in the border region between brazil and argentina |
| topic | Hantavírus Soroprevalência de hantavirose em Santa Catarina Morbidade |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000200001&lng=en&tlng=en |
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