Angiogenic Gene Signature Derived from Subtype Specific Cell Models Segregate Proneural and Mesenchymal Glioblastoma

Angiogenic Gene Signature Derived from Subtype Specific Cell Models Segregate Proneural and Mesenchymal Glioblastoma

Intertumoral molecular heterogeneity in glioblastoma identifies four major subtypes based on expression of molecular markers. Among them, the two clinically interrelated subtypes, proneural and mesenchymal, are the most aggressive with proneural liable for conversion to mesenchymal upon therapy. Usi...

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Bibliographic Details
Main Authors:	Aman Sharma, Ajinkya Bendre, Abir Mondal, Dattatraya Muzumdar, Naina Goel, Anjali Shiras
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-07-01
Series:	Frontiers in Oncology
Subjects:	angiogenesis intertumoral heterogeneity angiopoietins glioma stem cells biomarker
Online Access:	http://journal.frontiersin.org/article/10.3389/fonc.2017.00146/full

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