Clinical evaluation of pulmonary hypertension using patient-reported outcomes: a cross-sectional study
Abstract Background Patients with pulmonary hypertension (PH) have progressive and disabling symptoms, as well as a burden of treatments and a difficult clinical evaluation that make health-related quality of life a particularly relevant endpoint in this disease. The objective of the study was to ev...
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| Format: | Article |
| Language: | English |
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BMC
2021-02-01
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| Series: | BMC Pulmonary Medicine |
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| Online Access: | https://doi.org/10.1186/s12890-021-01416-7 |
| _version_ | 1818388077722206208 |
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| author | Miguel Ángel Amor-García Sara Ibáñez-García Xandra García-González Teresa Mombiela Cristina Villanueva-Bueno Ana Herranz-Alonso María Sanjurjo-Sáez |
| author_facet | Miguel Ángel Amor-García Sara Ibáñez-García Xandra García-González Teresa Mombiela Cristina Villanueva-Bueno Ana Herranz-Alonso María Sanjurjo-Sáez |
| author_sort | Miguel Ángel Amor-García |
| collection | DOAJ |
| description | Abstract Background Patients with pulmonary hypertension (PH) have progressive and disabling symptoms, as well as a burden of treatments and a difficult clinical evaluation that make health-related quality of life a particularly relevant endpoint in this disease. The objective of the study was to evaluate patient-reported outcomes of patients receiving specific treatment for PH in a tertiary hospital using a specific questionnaire (Cambridge Pulmonary Hypertension Outcome Review-CAMPHOR) in the pharmacy consultation. Methods A cross-sectional, observational, descriptive study was conducted. It included all patients receiving specific treatment for PH in a tertiary hospital in Madrid, Spain. The inclusion period comprised between August to December 2019. CAMPHOR questionnaires containing three domains: symptoms, activities and quality of life were completed by the patients at the pharmacy consultation. Demographic and clinical variables, including WHO Functional Class (WHO FC), PH-specific tests and hemodynamic parameters, were recorded. Non-parametric analyses to assess relations between variables and CAMPHOR domains were performed. Results Thirty-six patients consented to participate in the study and completed the questionnaire. Median scores for symptoms, activities, and quality of life domains were 5.5 (2.5–10), 8.0 (4.5–10.5) and 3.5 (1–7.5), respectively. Statistically significant differences were found in the three domains when comparing by WHO FC, in the activities domain for 6-m walking test and in the quality of life domain for patients who had emergency visits or hospitalizations in the last year. Conclusions The CAMPHOR questionnaire could be useful as a complementary test to achieve an integrated evaluation of PH patients, who could complete it easily during their routine pharmacy visits. |
| first_indexed | 2024-12-14T04:20:06Z |
| format | Article |
| id | doaj.art-b8bf07f7ea6d44489603f2d4079c0311 |
| institution | Directory Open Access Journal |
| issn | 1471-2466 |
| language | English |
| last_indexed | 2024-12-14T04:20:06Z |
| publishDate | 2021-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pulmonary Medicine |
| spelling | doaj.art-b8bf07f7ea6d44489603f2d4079c03112022-12-21T23:17:23ZengBMCBMC Pulmonary Medicine1471-24662021-02-012111910.1186/s12890-021-01416-7Clinical evaluation of pulmonary hypertension using patient-reported outcomes: a cross-sectional studyMiguel Ángel Amor-García0Sara Ibáñez-García1Xandra García-González2Teresa Mombiela3Cristina Villanueva-Bueno4Ana Herranz-Alonso5María Sanjurjo-Sáez6Pharmacy Service, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio MarañónPharmacy Service, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio MarañónPharmacy Service, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio MarañónDepartment of Cardiology, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio MarañónPharmacy Service, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio MarañónPharmacy Service, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio MarañónPharmacy Service, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio MarañónAbstract Background Patients with pulmonary hypertension (PH) have progressive and disabling symptoms, as well as a burden of treatments and a difficult clinical evaluation that make health-related quality of life a particularly relevant endpoint in this disease. The objective of the study was to evaluate patient-reported outcomes of patients receiving specific treatment for PH in a tertiary hospital using a specific questionnaire (Cambridge Pulmonary Hypertension Outcome Review-CAMPHOR) in the pharmacy consultation. Methods A cross-sectional, observational, descriptive study was conducted. It included all patients receiving specific treatment for PH in a tertiary hospital in Madrid, Spain. The inclusion period comprised between August to December 2019. CAMPHOR questionnaires containing three domains: symptoms, activities and quality of life were completed by the patients at the pharmacy consultation. Demographic and clinical variables, including WHO Functional Class (WHO FC), PH-specific tests and hemodynamic parameters, were recorded. Non-parametric analyses to assess relations between variables and CAMPHOR domains were performed. Results Thirty-six patients consented to participate in the study and completed the questionnaire. Median scores for symptoms, activities, and quality of life domains were 5.5 (2.5–10), 8.0 (4.5–10.5) and 3.5 (1–7.5), respectively. Statistically significant differences were found in the three domains when comparing by WHO FC, in the activities domain for 6-m walking test and in the quality of life domain for patients who had emergency visits or hospitalizations in the last year. Conclusions The CAMPHOR questionnaire could be useful as a complementary test to achieve an integrated evaluation of PH patients, who could complete it easily during their routine pharmacy visits.https://doi.org/10.1186/s12890-021-01416-7Pulmonary hypertensionQuality of lifeHealth-related quality of lifeCAMPHORPharmacy services |
| spellingShingle | Miguel Ángel Amor-García Sara Ibáñez-García Xandra García-González Teresa Mombiela Cristina Villanueva-Bueno Ana Herranz-Alonso María Sanjurjo-Sáez Clinical evaluation of pulmonary hypertension using patient-reported outcomes: a cross-sectional study BMC Pulmonary Medicine Pulmonary hypertension Quality of life Health-related quality of life CAMPHOR Pharmacy services |
| title | Clinical evaluation of pulmonary hypertension using patient-reported outcomes: a cross-sectional study |
| title_full | Clinical evaluation of pulmonary hypertension using patient-reported outcomes: a cross-sectional study |
| title_fullStr | Clinical evaluation of pulmonary hypertension using patient-reported outcomes: a cross-sectional study |
| title_full_unstemmed | Clinical evaluation of pulmonary hypertension using patient-reported outcomes: a cross-sectional study |
| title_short | Clinical evaluation of pulmonary hypertension using patient-reported outcomes: a cross-sectional study |
| title_sort | clinical evaluation of pulmonary hypertension using patient reported outcomes a cross sectional study |
| topic | Pulmonary hypertension Quality of life Health-related quality of life CAMPHOR Pharmacy services |
| url | https://doi.org/10.1186/s12890-021-01416-7 |
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