Bat Astrovirus in Mozambique
Abstract Astroviruses (AstVs) are responsible for infection of a large diversity of mammalian and avian species, including bats, aquatic birds, livestock and humans. We investigated AstVs circulation in bats in Mozambique and Mayotte, a small island in the Comoros Archipelago located between east Af...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-06-01
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| Series: | Virology Journal |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12985-018-1011-x |
| _version_ | 1818542286313619456 |
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| author | Flora Hoarau Gildas Le Minter Léa Joffrin M. Corrie Schoeman Erwan Lagadec Beza Ramasindrazana Andréa Dos Santos Steven M. Goodman Eduardo S. Gudo Patrick Mavingui Camille Lebarbenchon |
| author_facet | Flora Hoarau Gildas Le Minter Léa Joffrin M. Corrie Schoeman Erwan Lagadec Beza Ramasindrazana Andréa Dos Santos Steven M. Goodman Eduardo S. Gudo Patrick Mavingui Camille Lebarbenchon |
| author_sort | Flora Hoarau |
| collection | DOAJ |
| description | Abstract Astroviruses (AstVs) are responsible for infection of a large diversity of mammalian and avian species, including bats, aquatic birds, livestock and humans. We investigated AstVs circulation in bats in Mozambique and Mayotte, a small island in the Comoros Archipelago located between east Africa and Madagascar. Biological material was collected from 338 bats and tested for the presence of the AstV RNA-dependent RNA-polymerase gene with a pan-AstV semi-nested polymerase chain reaction assay. None of the 79 samples obtained from Mayotte bats (Pteropus seychellensis comorensis and Chaerephon pusillus) tested positive; however, 20.1% of bats sampled in Mozambique shed AstVs at the time of sampling and significant interspecific variation in the proportion of positive bats was detected. Many AstVs sequences obtained from a given bat species clustered in different phylogenetic lineages, while others seem to reflect some level of host-virus association, but also with AstVs previously reported from Malagasy bats. Our findings support active circulation of a large diversity of AstVs in bats in the western Indian Ocean islands, including the southeastern African coast, and highlight the need for more detailed assessment of its risk of zoonotic transmission to human populations. |
| first_indexed | 2024-12-11T22:20:05Z |
| format | Article |
| id | doaj.art-b8bf5559a32b42f8a4a1d889ef309772 |
| institution | Directory Open Access Journal |
| issn | 1743-422X |
| language | English |
| last_indexed | 2024-12-11T22:20:05Z |
| publishDate | 2018-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Virology Journal |
| spelling | doaj.art-b8bf5559a32b42f8a4a1d889ef3097722022-12-22T00:48:29ZengBMCVirology Journal1743-422X2018-06-011511510.1186/s12985-018-1011-xBat Astrovirus in MozambiqueFlora Hoarau0Gildas Le Minter1Léa Joffrin2M. Corrie Schoeman3Erwan Lagadec4Beza Ramasindrazana5Andréa Dos Santos6Steven M. Goodman7Eduardo S. Gudo8Patrick Mavingui9Camille Lebarbenchon10Université de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT), INSERM 1187, CNRS 9192, IRD 249Université de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT), INSERM 1187, CNRS 9192, IRD 249Université de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT), INSERM 1187, CNRS 9192, IRD 249School of Life Sciences, Biological Sciences Building, University of Kwa-Zulu NatalUniversité de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT), INSERM 1187, CNRS 9192, IRD 249Université de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT), INSERM 1187, CNRS 9192, IRD 249Veterinary Faculty, Eduardo Mondlane UniversityAssociation VahatraInstituto Nacional de SaúdeUniversité de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT), INSERM 1187, CNRS 9192, IRD 249Université de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT), INSERM 1187, CNRS 9192, IRD 249Abstract Astroviruses (AstVs) are responsible for infection of a large diversity of mammalian and avian species, including bats, aquatic birds, livestock and humans. We investigated AstVs circulation in bats in Mozambique and Mayotte, a small island in the Comoros Archipelago located between east Africa and Madagascar. Biological material was collected from 338 bats and tested for the presence of the AstV RNA-dependent RNA-polymerase gene with a pan-AstV semi-nested polymerase chain reaction assay. None of the 79 samples obtained from Mayotte bats (Pteropus seychellensis comorensis and Chaerephon pusillus) tested positive; however, 20.1% of bats sampled in Mozambique shed AstVs at the time of sampling and significant interspecific variation in the proportion of positive bats was detected. Many AstVs sequences obtained from a given bat species clustered in different phylogenetic lineages, while others seem to reflect some level of host-virus association, but also with AstVs previously reported from Malagasy bats. Our findings support active circulation of a large diversity of AstVs in bats in the western Indian Ocean islands, including the southeastern African coast, and highlight the need for more detailed assessment of its risk of zoonotic transmission to human populations.http://link.springer.com/article/10.1186/s12985-018-1011-xMammastrovirusMayotteMozambiqueMadagascarTriaenops afer |
| spellingShingle | Flora Hoarau Gildas Le Minter Léa Joffrin M. Corrie Schoeman Erwan Lagadec Beza Ramasindrazana Andréa Dos Santos Steven M. Goodman Eduardo S. Gudo Patrick Mavingui Camille Lebarbenchon Bat Astrovirus in Mozambique Virology Journal Mammastrovirus Mayotte Mozambique Madagascar Triaenops afer |
| title | Bat Astrovirus in Mozambique |
| title_full | Bat Astrovirus in Mozambique |
| title_fullStr | Bat Astrovirus in Mozambique |
| title_full_unstemmed | Bat Astrovirus in Mozambique |
| title_short | Bat Astrovirus in Mozambique |
| title_sort | bat astrovirus in mozambique |
| topic | Mammastrovirus Mayotte Mozambique Madagascar Triaenops afer |
| url | http://link.springer.com/article/10.1186/s12985-018-1011-x |
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